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Objective: The opioid epidemic is a national public health emergency that requires a comprehensive approach to reduce opioid-related deaths. Proper and timely disposal of unused prescription opioids is one method to deter improper use of these medications and prevent overdose. The objective of this study was to understand how recommendations for disposing of unused prescription opioids, including both take-back programs and toilet disposal, are communicated to the public.
Methods: Two hundred sixty-three US newspaper articles published between January 1, 2014, and June 30, 2017, containing information on opioids and take-back programs were found using LexisNexis. Using content analysis, articles were coded for the presentation of and recommendation for opioid disposal practices, beliefs about environmental harm from toilet disposal, and additional strategies to reduce opioid supply. The entity responsible for the statement was also captured.
Results: Take-back programs were presented as a recommended disposal strategy for unused prescription opioids in 88.6% of coded articles. Toilet disposal was presented as a recommended disposal strategy for unused prescription opioids in 3.4% of articles and as harmful to the environment in 16.0% of articles. Individuals from health care, government, and law enforcement were primarily involved in discussing opioid disposal practices.
Conclusions: Although toilet disposal is recommended by the US Food and Drug Administration (FDA) for disposal of unused prescription opioids when a take-back program is not readily available, it was infrequently presented or recommended in news media articles. These results highlight the importance of improving communication of FDA guidelines for opioid disposal in the media, particularly by health care providers, government employees, and law enforcement officials.
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http://dx.doi.org/10.1093/pm/pnz104 | DOI Listing |
Explor Res Clin Soc Pharm
December 2025
School of Medicine, Collage of Health Sciences, Salale University, Ethiopia.
Background: Unused medicines present significant public health, environmental risks and economic challenges. Understanding their prevalence and determinants is crucial for designing appropriate interventions. This systematic review and meta-analysis aimed to estimate the pooled prevalence and determinants of unused medicines among households in Ethiopia.
View Article and Find Full Text PDFAdv Cancer Educ Qual Improv
January 2025
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center.
Background: Surgeons provide up to 10% of total opioid prescriptions across all specialties, and more than one-third of surgeon-prescribed medications are opioids. Patient-reported opioid consumption and risk of persistent opioid use beyond the postoperative recovery period correlate with the initial opioid quantity prescribed at discharge. Interventions to reduce postoperative opioid prescribing have demonstrated no adverse effects on pain control or increased need for prescription refill; however, in the absence of standardized prescription protocols, opioid prescribing practices vary widely.
View Article and Find Full Text PDFJAMIA Open
June 2025
Communication Practice Area, RTI International, Research Triangle Park, NC 27709, United States.
Objective: To describe challenges and solutions for calculating longitudinal daily opioid dose in morphine milligram equivalents from electronic health record prescriptions for a clinical trial of voluntary opioid reduction in patients with chronic non-cancer pain.
Materials And Methods: Researchers obtained opioid prescriptions for 525 participants from the National Patient-Centered Clinical Research Network datamart at three health systems. Daily opioid dose was calculated using dose conversions and summing across prescriptions after applying assumptions, reviewing suspect prescribing patterns, and removing spurious prescriptions.
Arthroplast Today
June 2025
Colorado Joint Replacement, Denver, CO, USA.
Background: Reducing unused prescribed opioids following arthroplasty procedures remains a challenge. The relationship between opioid consumption and age has seldom been investigated. We hypothesize that older patients consume fewer narcotic medications than younger patients following primary unilateral total knee arthroplasty (TKA).
View Article and Find Full Text PDFJMIR Res Protoc
June 2025
Department of Health Education and Promotion, College of Health and Human Performance, East Carolina University, Greenville, NC, United States.
Background: Pharmacies can implement multiple strategies, including medication disposal programs (eg, disposal boxes, deactivation products, and mail-back envelopes) and offering over-the-counter naloxone, to prevent nonmedical opioid use and overdose. The quantity of opioid prescriptions dispensed in the United States is so high that every other adult could receive one opioid prescription per year. Many of these opioids go unused and are kept in homes rather than disposed of after ceasing use.
View Article and Find Full Text PDF