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http://dx.doi.org/10.1128/AAC.02282-18 | DOI Listing |
PLOS Glob Public Health
August 2025
Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America.
Nursing home acquired pneumonia (NHAP), and its subset - aspiration-associated pneumonia, is a leading cause of morbidity and mortality among residents in long-term care facilities (LTCFs). Understanding colonization dynamics of respiratory pathogens in LTCF residents is essential for effective infection control. This study examines the longitudinal trends in prevalence, persistence, bacterial load, and co-colonization patterns of five respiratory pathogens in three LTCFs in Phoenix, Arizona.
View Article and Find Full Text PDFJAC Antimicrob Resist
June 2025
Microbiology Research Unit, Division of Oral Biosciences, Dublin Dental University Hospital, University of Dublin, Trinity College Dublin, Lincoln Place, Dublin D02 F859, Ireland.
Background: Vancomycin-resistant (VREfm) are significant nosocomial pathogens. Irish VREfm comprise diverse -encoding ST80-complex type (CT) lineages. Recent studies indicate that within-patient VREfm diversity could confound surveillance.
View Article and Find Full Text PDFGut Microbes
December 2025
Gut Microbiology Group, Rowett Institute, University of Aberdeen, Aberdeen, UK.
is one of the most abundant and important butyrate-producing human gut anaerobic bacteria that plays an important role in maintaining health and is a potential next-generation probiotic. We investigated the pangenome of 16 distinct strains, isolated over several decades, identifying local and time-specific adaptations. More than 50% of the genes in each individual strain were assigned to the core genome, and 77% of the cloud genes were unique to individual strains, revealing the high level of genome conservation.
View Article and Find Full Text PDFMicrob Genom
March 2025
Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA.
(SA) is an opportunistic pathogen and human commensal that is frequently present in the upper respiratory tract, gastrointestinal tract and skin. While SA can cause diseases ranging from minor skin infections to life-threatening bacteraemia, it can also be carried asymptomatically. Indigenous individuals in the Southwest USA experience high rates of invasive SA disease.
View Article and Find Full Text PDFbioRxiv
December 2024
Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America.
Nursing home acquired pneumonia (NHAP), and its subset - aspiration-associated pneumonia, is a leading cause of morbidity and mortality among residents in long-term care facilities (LTCFs). Understanding colonization dynamics of respiratory pathogens in LTCF residents is essential for effective infection control. This study examines the longitudinal trends in prevalence, persistence, bacterial load, and co-colonization patterns of five respiratory pathogens in three LTCFs in Phoenix, Arizona.
View Article and Find Full Text PDF