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http://dx.doi.org/10.1111/tbj.13281 | DOI Listing |
ACS Appl Bio Mater
September 2025
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
The generation of reactive oxygen species (ROS) through nanozyme-mediated sonocatalytic therapy has demonstrated remarkable therapeutic efficacy in the field of cancer. Nevertheless, it remains a significant challenge for nanozymes with a single catalytic active center to generate sufficient ROS via Fenton or Fenton-like reactions to effectively induce tumor cell death. In order to enhance the catalytic efficacy, we devised and synthesized a multiple active centre and mitochondrial-targeted perovskite nanozyme (NCFP), doped with cobalt (Co) element, and incorporated 4-carboxybutyltriphenylphosphonium bromide (TPP) as a mitochondrial targeting marker for ultrasound (US)-assisted enzyme-like catalytic treatment of tumors.
View Article and Find Full Text PDFJ Phys Chem Lett
September 2025
College of Materials Science and Engineering, Sichuan University, No. 24 South Section 1, Yihuan Road, Chengdu 610065, P. R. China.
Aqueous zinc-ion microbatteries exhibit promising prospects for wearable devices due to their high safety and cost-effectiveness but face challenges such as low energy density and short cycle life. To address these challenges, a dual-plating flexible Zn-Br microbattery was developed using freestanding MXene films as a zinc metal free anode. The MXene anode retains no redundant Zn, as Zn from the electrolyte undergoes deposition/stripping reactions on its substrate, thereby eliminating the necessity for excess zinc.
View Article and Find Full Text PDFJMIR Cancer
September 2025
iCARE Secure Data Environment & Digital Collaboration Space, NIHR Imperial Biomedical Research Centre, London, United Kingdom.
Background: Electronic health records (EHRs) are a cornerstone of modern health care delivery, but their current configuration often fragments information across systems, impeding timely and effective clinical decision-making. In gynecological oncology, where care involves complex, multidisciplinary coordination, these limitations can significantly impact the quality and efficiency of patient management. Few studies have examined how EHR systems support clinical decision-making from the perspective of end users.
View Article and Find Full Text PDFJ Med Internet Res
September 2025
Centre Hospitalier Rives de Seine, Courbevoie, France.
Background: Every year in France, 40% of people aged ≥80 years are hospitalized, with an average length of hospital stay of 25 days and a readmission rate of 14% to 30% within the month following discharge. This situation is putting pressure on the health care system, encouraging the reinforcement of home care to reduce avoidable hospitalization. The EPOCA remote patient monitoring (RPM) system is a medical and social telehealth solution specialized in RPM, teleconsultation, tele-expertise, and care coordination in emergency medicine and geriatrics.
View Article and Find Full Text PDFJMIR Rehabil Assist Technol
September 2025
Department of Computer Science, Faculty of Technology, Art and Design, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Background: Over the past decade, the proportion of the world's population aged ≥65 years has grown exponentially, presenting significant challenges, such as social isolation and loneliness among this population. Assistive technologies have shown potential in enhancing the quality of life for older adults by improving their physical, cognitive, and communication abilities. Research has shown that smart televisions are user-friendly and commonly used among older adults.
View Article and Find Full Text PDF