The synergistic effect of hydroalcoholic extracts of , and their active components carvacrol and hypericin against .

Aim: This study was designed to evaluate the synergistic activities of hydroalcoholic extracts of medicinal plants and and their active components, carvacrol and hypericin against .

Methods: The synergistic effects of the plants, as well as carvacrol and hypericin, were examined using a checkered method against (ATCC 12600).

Results: A fractional inhibitory concentration of 0.5 was obtained for combination of and and 0.49 for combination of the active ingredients carvacrol and hypericin, both of which indicated a synergistic effect.

Conclusion: This preliminary evaluation demonstrated a synergistic property of and extracts in treating infection. This study indicates that combination of the plants, as well as combination of carvacrol and hypericin, might be used as a new antibacterial strategy against .