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http://dx.doi.org/10.1111/srt.12658 | DOI Listing |
Int J Dermatol
September 2025
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Introduction: Cutaneous scalp metastases from breast carcinoma (CMBC) represent an uncommon manifestation of metastatic disease, with heterogeneous clinical presentations, including nodular or infiltrative lesions and scarring alopecia (alopecia neoplastica). The absence of standardized diagnostic criteria, particularly for alopecic phenotypes, poses challenges to early recognition of CMBC, which may represent either the first indication of neoplastic progression or a late recurrence.
Materials And Methods: We retrospectively analyzed a multicenter cohort of 15 patients with histologically confirmed CMBC.
Exp Dermatol
August 2025
The Kittner Skin Cancer Screening & Research Institute, Sheba Medical Center, Ramat Gan and School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Negative pigment network (NPN) is a dermoscopic structure frequently associated with melanoma. Though commonly observed in Spitz naevi (SN) and Spitzoid melanoma (SM), its reflectance confocal microscopy (RCM) correlates have been primarily studied in non-Spitzoid melanocytic neoplasms. This study aimed to identify clinical, dermoscopic, and RCM features associated with dermoscopic NPN in Spitzoid neoplasms and explore its histopathological correlates.
View Article and Find Full Text PDFClin Exp Dermatol
August 2025
Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Skin Cancer Center, Reggio Emilia, Italy.
Background: Familial melanoma represents approximately 10% of cutaneous melanomas. Individuals with pathogenic germline variants have a higher risk of developing multiple primary melanomas (MPM). However, differences in clinical, dermoscopic, and reflectance confocal microscopy (RCM) features between variant carriers and non-carriers are not well established.
View Article and Find Full Text PDFIndian Dermatol Online J
September 2025
Department of Dermatology, Venereology and Leprosy, SRM Medical College Hospital and Research Centre, Kattankulathur Campus, Chengalpattu, Tamil Nadu, India.
Benign lichenoid keratosis (BLK), also known as lichen planus-like keratosis, is a benign cutaneous lesion of unknown etiology with overlapping clinical and dermoscopic features with malignant lesions. A 52-year-old female presented with a 10- years history of a single asymptomatic lesion on the left gluteal region not associated with loss of weight, loss of appetite, or other systemic symptoms. Clinical examination revealed a single well-defined violaceous to hyperpigmented plaque of approximately 4 cm × 3 cm in size, on the lateral aspect of the left gluteal region.
View Article and Find Full Text PDFDermatol Pract Concept
July 2025
Dermatology Clinic, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.
Introduction: Magnified dermoscopy (MD), or optical super-high magnification dermoscopy, is an emerging technique in dermatology.
Objectives: The study aimed to evaluate the distribution of conventional dermoscopy, MD, and reflectance confocal microscopy (RCM) features in dermoscopically equivocal pigmented lesions and to estimate their diagnostic accuracy.
Methods: A retrospective analysis of conventional dermoscopic (20x), MD (400x), and RCM images of dermoscopically equivocal pigmented lesions, diagnosed as either nevi or melanoma, was performed.