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Nowadays, pesticide residues constitute an increasing public health concern. Cholinesterases, acetylcholinesterase, and butyrylcholinesterase, are reported to be involved in detoxification processes owing to their capability of scavenging organophosphates and carbamates. Thus, these enzymes are targeted for the discovery of sensors aiming at detecting pesticide residues. In recent years, cholinesterase-based biosensors have attracted more and more attention in the detection of pesticides. Herein, this review describes the recent progress on the engineering of cholinesterases and the development of the corresponding sensors that could be used for the detection of organophosphorus pesticide residues.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312092 | PMC |
http://dx.doi.org/10.3390/s18124281 | DOI Listing |
The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State Austria, for the pesticide active substance pinoxaden are reported. The context of the peer review was that requested by the European Commission following the submission and evaluation of confirmatory information in the areas of environmental fate, mammalian toxicology and residues. The conclusions were reached on the basis of the evaluation of the representative uses of pinoxaden as a herbicide in winter and spring cereals.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
September 2025
Science Faculty, Department of Biology, Firat University: Firat Universitesi, Elazığ, Türkiye.
Deltamethrin (DM) and cypermethrin (CM) are widely used pesticides belonging to the pyrethroid class. Antagonistic microorganisms are preferred as biocontrol agents to mitigate pesticide toxicity. Probiotic bacteria and yeasts are the primary biocontrol agents employed for this purpose.
View Article and Find Full Text PDFFront Pharmacol
August 2025
Shenzhen Institute for drug Control, Shenzhen, China.
Introduction: The procedural complexity and time-consuming of conventional pesticide residue detection methods in traditional Chinese medicines (TCMs) significantly impeded their application in modern systems. To address this, this study presented an innovative dual-mode sensor driven by Cu/Cu redox-cycling, which achieved efficient signal transduction from enzyme inhibition to optical response for rapid acetylcholinesterase (AChE) activity and organophosphorus pesticide (OP) residue detection.
Methods: The AB-Cu NPs sensor, a dynamic redox-responsive system, was constructed via coordination-driven assembly of Azo-Bodipy 685 (AB 685) and Cu.
Pestic Biochem Physiol
November 2025
Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi, China; Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural
The olfactory system of insects plays a vital role in their survival by enabling them to detect chemical cues and adapt to changing environments. The rape stem weevil, Ceutorhynchus asper, is a significant pest posing a challenge for rapeseed production due to its destructive feeding habit and increasing resistance to insecticides. So far, there's still limited knowledge about structure and function of odorant binding proteins (OBPs) in beetles like C.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Key Laboratory of Forest Disaster Warning and Control of Yunnan Province, Southwest Forestry University, Kunming 650224, China. Electronic address:
The cerambycid beetles are important components in the terrestrial ecosystem as they play a dual role in both degrading dying trees and killing healthy plants. The factors including human activity, habitat contraction, climate changes and pesticide use have been shaping the adaptation of beetles to host plants and the environment. As suggested in research on the functions of beetles' olfactory proteins, odorant binding proteins (OBPs) have been found to be involved in insecticide resistance other than chemoreception.
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