Global challenges faced by engineered genes in soybean ( L.) in the twenty-first century.

The most important insect pests causing severe economic damages to soybean ( L.) production worldwide are (), (), (), (), (Walker, Noctuidae), (Walker, Noctuidae), (Stoll, Noctuidae), (Smith; Noctuidae), (Hübner, Noctuidae), (Boddie; Noctuidae) and (Hymenoptera,Platygastidae). Despite the success of biotech ()/herbicide tolerance (HT)-soybean in the past decade in terms of output, unforeseen mitigated performances have been observed due to changes in climatic events that favors the emergence of insect resistance. Thus, there is a need to develop hybrids with elaborated gene stacking to avert the upsurge in insect field tolerance to crystal (Cry) toxins in -soybean. This study covers the performance of important commercial transgenic soybean developed to outwit destructive insects. New gene stacking soybean events such as -, - and -soybean (DAS-81419-2, Conkesta™ technology), and MON-87751-7 × MON-87701-2 × MON 87708 × MON 89788 (bearing [], ) are being approved and deployed in fields. Following this deployment trend, we recommend herein that plant-mediated RNA interference into soybean, and the application of RNA-based pesticides that is complemented by other best agricultural practices such as refuge compliance, and periodic application of low-level insecticides could maximize trait durability in -soybean production in the twenty-first century.