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http://dx.doi.org/10.21037/tlcr.2018.09.06 | DOI Listing |
Comp Biochem Physiol C Toxicol Pharmacol
December 2025
Department of Plant Medicine, College of Agriculture, Life and Environment Sciences, Chungbuk National University, Cheongju 28644, Republic of Korea. Electronic address:
To test the hypothesis that the expression profiles, evolutionary patterns, and functionalities of anti-microbial peptides (AMPs) and proteins in some hymenopteran and heteropteran species are influenced by their distinct ecological traits, we conducted venom and salivary gland-specific transcriptome analyses. We compared the expression and evolutionary patterns of anti-microbial peptide and proteins across 22 hymenopteran and 9 heteropteran species. Additionally, we investigated the structural properties of selected defensins and assessed their anti-microbial and hemolytic activities.
View Article and Find Full Text PDFMar Drugs
June 2025
Marine Science Institute, University of the Philippines, Quezon City 1101, Philippines.
A large majority of cone snails (a species in the genus ) are vermivorous (worm-hunting), but the diversity and bioactivity of their venom peptides remain largely unexplored. In this study, we report the first venom gland transcriptomes from two species in the clade, and , and a new transcriptome from a specimen collected in the Philippines. From the set of assembled sequences, a total of 225 , 121 , and 168 putative peptide toxin transcripts were identified, which were assigned to 27 canonical gene superfamilies in and 24 in and in .
View Article and Find Full Text PDFCamouflage is a critical survival strategy that helps to evade predation and increase hunting success. Background matching and disruptive colouration are different camouflage strategies that are subject to different selective pressures and can drive divergence in their associated traits such as colour pattern and behaviour. This study tested whether two closely related reef fish species (Hypoplectrus spp.
View Article and Find Full Text PDFBMC Genomics
February 2025
Wildlife Research Unit (UIRCP-UCO), University of Cordoba, Cordoba, Spain.
Mate competition encourages individuals to modulate characters involved in mating success. Adult Iberian red deer (Cervus elaphus hispanicus) males show a dark ventral patch (DVP) that plays a central role in mating rivalry, whose size and chemical compounds varied according to the level of male-male competition within the population. In the pigmentation of the DVP appears, after urinary excretion, a molecule called DOPEG originating from the metabolism of norepinephrine, leading us to investigate whether differential expression mechanisms of key genes dopamine B-hydroxylase (DBH) and tyrosine hydroxylase (TH), encoding enzymes catalyzing the process can be sensitive to different competitive population situations and responsible for the plastic development of the DVP in red deer.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2024
Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80309.
As ambush-hunting predators that consume large prey after long intervals of fasting, Burmese pythons evolved with unique adaptations for modulating organ structure and function. Among these is cardiac hypertrophy that develops within three days following a meal (Andersen et al., 2005, Secor, 2008), which we previously showed was initiated by circulating growth factors (Riquelme et al.
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