98%
921
2 minutes
20
On the basis of the chemistry of wine and the co-occurrence of 3-sulfanylhexan-1-ol (3-SH) and acetaldehyde, we investigated the existence of 2-methyl-4-propyl-1,3-oxathiane (1) and identified the presence of a single detectable geometric isomer, cis-1, in wines for the first time. A stable isotope dilution assay (SIDA) using headspace-solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS) was developed and validated, and used to quantitate cis-1 in a survey of wines, revealing a range from undetectable (limit of detection = 2.6 ng/L) to 460 ng/L. The odor detection threshold of 1 (using a standard comprising 85% cis-1 and 15% trans-1) in neutral white wine was determined to be 7.1 μg/L. Despite cis-1 not appearing above the determined sensory threshold in the studied wines, the findings demonstrated the presence of a new volatile sulfur compound with a strong correlation to 3-SH concentration ( r = 0.72), showing that cis-1 has potential implications for the fate of the important wine aroma compound 3-SH.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1021/acs.jafc.8b04027 | DOI Listing |
J Med Internet Res
September 2025
The Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, 5 Sassoon Rd, Sandy Bay, Hong Kong, 999077, China (Hong Kong), 852 2831 5232.
Background: Online text-based counseling services are becoming increasingly popular. However, their text-based nature and anonymity pose challenges in tracking and understanding shifts in help-seekers' emotional experience within a session. These characteristics make it difficult for service providers to tailor interventions to individual needs, potentially diminishing service effectiveness and user satisfaction.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Anaesthesiology, Nanfang Hospital, Southern Medical University; The key Laboratory of Precision Anaesthesia & perioperative Organ Protection, Guangzhou, Guangdong, China.
Background: Myocardial injury after noncardiac surgery (MINS) is associated with poor prognosis. The effect of different occurrence time of MINS on long-term functional capacity remains unclear in population with high cardiovascular risk.
Patients And Methods: This cohort study included adult patients with increased cardiovascular risk undergoing elective major noncardiac surgery from June 2019 to September 2021.
Toxics
July 2025
Battelle Memorial Institute, 505 King Ave, Columbus, OH 43201, USA.
Microplastics (MPs) and nanoplastics (NPs) can affect microbial abundance and activity, likely by damaging cell membrane components. While their effects on anaerobic digestion are known, less is understood about their impact on microbes involved in contaminant bioremediation. Chlorinated volatile organic contaminants (CVOCs) such as tetrachloroethene (PCE) and explosives like hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) are common in the environment, and their bioremediation is a promising cleanup strategy.
View Article and Find Full Text PDFCardiovasc Diabetol
August 2025
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, PR China.
Background: The global burden of type 2 diabetes mellitus (T2DM) is increasing, particularly in resource-limited settings like rural China. Although traditional blood glucose remains an essential measurement for diabetes screening, Atherogenic Index of Plasma (AIP) is emerging as a complementary predictor of T2DM risk. Over time, however, the association between AIP and T2DM risk remains insufficiently understood.
View Article and Find Full Text PDFEur J Epidemiol
August 2025
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.
Previous studies on the association of potentially inappropriate medication (PIM) use with hospitalization risk and all-cause mortality among older adults were prone to confounding and biases. Using data from 217,111 participants of the population-based United Kingdom Biobank, aged 60-69 years, including 95,187 participants with primary care data linkage, the main analysis was a prospective new user design with 1:1 propensity-score stratified by indication matching of new PIM users and new appropriate medication (AM) users (assessed with the EURO-FORTA list). Results were compared to previous approaches with a prevalent user design and a new user design without propensity score matching.
View Article and Find Full Text PDF