Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Four unprecedented guaiane dimers, xylopsides A-D (1-4), were isolated and identified from the roots of Xylopia vielana. The structures of 1-4 were elucidated by spectroscopic analysis, Cu Kα X-ray crystallography and CD spectra. 1-4 showed two bridged pentacyclic skeletons between two guaiane-type sesquiterpenes, which were characterized as two different bridged ring systems. Among these compounds, 4 exhibited a moderate inhibitory activity against the production of nitric oxide with an IC50 value of 25.7 μM in RAW264.7 cells stimulated by LPS.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c8ob01689e | DOI Listing |
Publication Analysis
Top Keywords
xylopsides a-d
8
guaiane dimers
8
bridged pentacyclic
8
pentacyclic skeletons
8
xylopia vielana
8
a-d rare
4
rare guaiane
4
dimers unique
4
unique bridged
4
skeletons xylopia
4