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Background: Le Fort I maxillary advancements affect nasal proportions. However, there are no data on the three-dimensional nasal changes that occur with differential lateral plane adjustment (clockwise and counterclockwise movements) during Le Fort I maxillary advancements. This study analyzes and compares nasolabial soft-tissue changes after Le Fort I clockwise and counterclockwise repositioning.
Methods: Single-piece Le Fort I advancements were included. A retrospective study of patients split into clockwise and counterclockwise groups was performed. Preoperative and postoperative three-dimensional photographs (VECTRA 3D) were analyzed. Nasolabial anthropometric measurements were recorded using Mirror software. Statistical analysis involved paired t test to compare preoperative and postoperative measurements.
Results: Twenty-four patients were evaluated (12 per group), with 22 distinct nasolabial relationships measured. Counterclockwise movement showed a statistically significant increase in alar width (3.6 mm; p < 0.001), alar base width (1.6 mm; p = 0.009), oral width (3.2 mm; p = 0.02), and lip projection (3.4 mm; p = 0.04). Clockwise movement showed no statistically significant changes, with the largest position changes noted in alar width (2.7 mm; p = 0.07) and alar base width (1.7 mm; p = 0.09).
Conclusions: Clockwise and counterclockwise Le Fort I advancements have a different effect on postoperative nasolabial morphology. Counterclockwise movements exhibit significant changes, widening the alar base and width and the oral and philtral widths. The impact on the nostril morphology and columella was similar between the groups. The differential impact on nasolabial appearance is important to recognize for treatment planning and patient counseling.
Clinical Question/level Of Evidence: Therapeutic, III.
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http://dx.doi.org/10.1097/PRS.0000000000004988 | DOI Listing |
Percept Mot Skills
September 2025
Department of Clinical Sciences, Otorhinolaryngology Head and Neck Surgery, Skåne University Hospital, Lund University, Lund, Sweden.
When patients experience peripheral vestibular or certain central disorders causing dizziness or vertigo, this is sometimes associated with experiencing also disrupted spatial orientation, which may be accentuated by exposure to a distorted visual environment. This study explores the impact of sensorimotor factors and sex on spatial orientation in sitting and standing positions. In the Rod-and-Frame test, the participant views a rod - with and without a surrounding tilted frame - and is assigned to align the rod vertically or horizontally.
View Article and Find Full Text PDFPharmaceuticals (Basel)
July 2025
Department of Biology, Faculty of Sciences, "Vasile Alecsandri" University of Bacau, Marasesti Street, 600115 Bacau, Romania.
: Pharmaceutical compounds frequently co-occur in environmental waters, but studies on their combined effects on animals and humans remain limited. The present study investigated the individual and combined short-term effects of ketoprofen (Kp, a nonsteroidal anti-inflammatory drug inhibiting cyclooxygenase-2), valproic acid (VPA, an anticonvulsant acting as a voltage-gated sodium channel modulator), and meropenem (Mp, a β-lactam antibiotic) at environmentally relevant concentrations on zebrafish behavior, acetylcholinesterase (AChE) activity, and oxidative status. : Adult zebrafish were exposed for 4 days to Kp, VPA, Mp, and their binary and ternary mixtures.
View Article and Find Full Text PDFSensors (Basel)
August 2025
Institute of Photonics Technologies, National Tsing Hua University, Hsinchu 300, Taiwan.
Hierarchical clustering analysis is applied to the positioning of two simultaneously-occurring intrusion events in the case of a dual Mach-Zehnder interferometer used for intrusion detection. To simulate the two intrusion events, the sensing fibers of the dual Mach-Zehnder interferometer are heavily knocked at two different positions simultaneously. Then the clockwise (CW) and counter-clockwise (CCW) signals are loaded into a personal computer through a data acquisition module, and analyzed by Fourier transform method for determination of the time delay between the two signals.
View Article and Find Full Text PDFJ Fluid Mech
March 2025
Mechanical and Aerospace Engineering Department, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Low inertia, pulsatile flows in highly distensible, viscoelastic vessels exist in many biological and engineering systems. However, many existing works focus on inertial, pulsatile flows in vessels with small deformations. As such, here we study the dynamics of a viscoelastic tube at large deformation conveying low Reynolds number, oscillatory flow using a fully-coupled fluid/structure interaction computational model.
View Article and Find Full Text PDFSmall
August 2025
CNRS, Bordeaux INP, ISM, UMR 5255, Univ. Bordeaux, Pessac, F-33607, France.
Light-emitting dynamic systems have attracted significant attention due to their wireless control, high sensitivity, short response-time, and self-mixing capability. Although, among the different propulsion mechanisms, magnetically-driven motion is a common approach, it requires the use of ferromagnetic components and complex electromagnetic set-ups. In this work, a wireless light-emitting monolayer graphene rotor is designed, powered by the synergetic effect between a magnetic field-enhanced electrophoretic propulsion mechanism and electrochemiluminescence (ECL) generated by the model [Ru(bpy)]⁺/tri-n-propylamine system.
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