Developing a 'multiPatchPET' system in GATE for a PET system design with irregular geometries.

This work modified the commonly used Monte Carlo tool package GATE by developing a new 'multiPatchPET' system so that GATE users can easily simulate PET systems with irregular geometries. The motivation was to design a brain PET scanner with high sensitivity. It is known that compact PET scanners with a large solid coverage angle can achieve high sensitivity with fewer scintillation detectors, and thus have the potential to provide better image quality in brain PET imaging than conventional ring PET scanners. However, considering a straightforward example with the largest possible solid angle, a spherical PET scanner is hard to manufacture. A more practical alternative would be a sphere-like polyhedral PET scanner with flat detector patches. Moreover, when monolithic scintillators are chosen to construct these flat detector modules, detection efficiency is further improved. Thus, we plan to design a sphere-like polyhedral PET scanner made up of monolithic scintillators. Unfortunately, in our design study, we found that simulating such a scanner with the latest GATE version (8.0) was not trivial, since no predefined systems could be used. In this work we introduced a 'multiPatchPET' system to GATE, which we and other GATE users will be able to use to develop PET scanners with any irregular geometry and any shape of patch. To validate our modification, a single block detector and an mCT scanner were simulated via both the original 'ecat' system and the new 'multiPatchPET' system. The results show no difference in terms of the detecting efficiency and reconstruction image. Then we used the 'multiPatchPET' system to simulate an 86 surface polyhedral brain PET scanner. Compared with two cylindrical brain scanners, the polyhedral brain scanner shows a higher sensitivity and has fewer noisy images. Thus, it was proved that our modification, which is accessible to the nuclear imaging research community, equipped GATE with a powerful and user-friendly tool to simulate complex scanners with irregular patches easily.