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The third international conference on Transposable Elements (ICTE) was held 16-19 April 2016 in Saint Malo, France. Organized by the French Transposition Community (Research group of the CNRS: "Mobile genetic elements: from mechanism to populations, an integrative approach") and the French Society of Genetics, the conference's goal was to bring together researchers who study transposition in diverse organisms, using multiple experimental approaches. The meeting gathered 180 participants from all around the world. Most of them contributed through poster presentations, invited talks and short talks selected from poster abstracts. The talks were organized into six scientific sessions: "Taming mobile DNA: self and non-self recognition"; "Trans-generational inheritance"; "Mobile DNA genome structure and organization, from molecular mechanisms to applications"; "Remembrance of (retro)transposon past: mobile DNA in genome evolution"; and finally "The yin and the yang of mobile DNA in human health".
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http://dx.doi.org/10.1186/s13100-016-0075-7 | DOI Listing |
Brief Bioinform
September 2025
Department of Computer Science, Hanyang University, 222 Wangsimni-ro, Seoul 04763, Republic of Korea.
Motivation: Mobile genetic elements (MGEs) play an important role in facilitating the acquisition of antibiotic resistance genes (ARGs) within microbial communities, significantly impacting the evolution of antibiotic resistance. Understanding the mechanism and trajectory of ARG acquisition requires a comprehensive analysis of the ARG-carrying mobilome-a collective set of MGEs carrying ARGs. However, identifying the mobilome within complex microbiomes poses considerable challenges.
View Article and Find Full Text PDFMol Plant Pathol
September 2025
Área de Genética, Facultad de Ciencias, Campus Teatinos s/n, Universidad de Málaga, Málaga, Spain.
The type III secretion system in Pseudomonas syringae complex pathogens delivers type III effectors (T3Es) into plant cells to manipulate host processes, enhance survival, and promote disease. While substantial research has focused on herbaceous pathogens, T3Es in strains infecting woody hosts are less understood. This study investigates the HopBL family of effectors in Pseudomonas savastanoi, a pathogen of woody plants.
View Article and Find Full Text PDFNeurotoxicology
September 2025
PERITOX Laboratory (UMR_I 01), UPJV/INERIS INERIS, MIV/TEAM, Verneuil-en-Halatte France University of Picardie Jules Verne, CURS, Amiens, France.
Health risks related to 900 MHz 2 G frequency exposure remain inconclusive under current regulatory standards. Research into potential long-term effects is ongoing, particularly as the use of mobile networks and wireless devices increases. This study investigates the effects of non-thermal exposure levels of mobile phone 900 MHz radiofrequency electromagnetic field (RF-EMF) on rodent neurodevelopment.
View Article and Find Full Text PDFPhilos Trans R Soc Lond B Biol Sci
September 2025
Laboratory of Molecular Microbiology, Global Health Institute, School of Life Sciences, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland.
the causative agent of cholera, has triggered seven pandemics, with the seventh pandemic emerging in 1961. The success of seventh pandemic El Tor (7PET) as a human pathogen is linked to its acquisition of mobile genetic elements (MGEs) like the CTXΦ prophage and pathogenicity island 1 (VPI-1). Additional MGEs, including VPI-2 and the seventh pandemic islands (VSP-I and VSP-II), are thought to have further enhanced the pathogen's virulence potential.
View Article and Find Full Text PDFMob DNA
September 2025
Laboratory of Cancer Epigenetics and Plasticity, Brown University, Providence, RI, USA.
Background: Glioblastoma, the most common primary malignant brain tumor, has a median survival of less than two years. This is due in part to a subpopulation of cells called glioblastoma stem cells (GSCs), which drive tumor recurrence. Transposable elements (TEs) are expressed at higher levels in cancer stem cells, enhancing the oncogenic potential and plasticity of cells through changes in gene expression, fusion transcript generation, and genomic rearrangement.
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