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Article Abstract
For the first time, an approach to 3,4-disubstituted thietes was developed through two complementary paths. While the first one relies on α-metalation, the second is based on direct C-H functionalization. A new library of sophisticated sulfur-containing four-membered rings is described, paving the way to new bioactive analogues and small heterocycle incorporation.
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| http://dx.doi.org/10.1021/acs.orglett.8b01961 | DOI Listing |
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