98%
921
2 minutes
20
Background: Minimally anchored Standard Rating Scales (SRSs), which are widely used in medical education, are hampered by suboptimal interrater reliability. Expert-derived frameworks, such as the Accreditation Council for Graduate Medical Education (ACGME) Milestones, may be helpful in defining level-specific anchors to use on rating scales.
Objective: We examined validity evidence for a Milestones-Based Rating Scale (MBRS) for scoring chart-stimulated recall (CSR).
Methods: Two 11-item scoring forms with either an MBRS or SRS were developed. Items and anchors for the MBRS were adapted from the ACGME Internal Medicine Milestones. Six CSR standardized videos were developed. Clinical faculty scored videos using either the MBRS or SRS and following a randomized crossover design. Reliability of the MBRS versus the SRS was compared using intraclass correlation.
Results: Twenty-two faculty were recruited for instrument testing. Some participants did not complete scoring, leaving a response rate of 15 faculty (7 in the MBRS group and 8 in the SRS group). A total of 529 ratings (number of items × number of scores) using SRSs and 540 using MBRSs were available. Percent agreement was higher for MBRSs for only 2 of 11 items-use of consultants (92 versus 75, = .019) and unique characteristics of patients (96 versus 79, = .011)-and the overall score (89 versus 82, < .001). Interrater agreement was 0.61 for MBRSs and 0.51 for SRSs.
Conclusions: Adding milestones to our rating form resulted in significant, but not substantial, improvement in intraclass correlation coefficient. Improvement was inconsistent across items.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008016 | PMC |
http://dx.doi.org/10.4300/JGME-D-17-00435.1 | DOI Listing |
Int J Nurs Knowl
September 2025
Luciano Feijão College, Sobral, Ceará, Brazil.
Purpose: To clinically validate the nursing diagnosis "Inadequate Nutritional Intake" based on elements identified within a specific situation theory framework in the context of children with cancer.
Methods: This is a diagnostic accuracy study following the Standards for Reporting Diagnostic Accuracy Studies (STARD) protocol. Specifically, it refers to the clinical validation phase of the nursing diagnosis Inadequate nutritional intake, using a cross-sectional design.
EMBO J
September 2025
School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.
Insulin resistance is a heritable risk factor for many chronic diseases; however, the genetic drivers remain elusive. In seeking these, we performed genetic mapping of insulin sensitivity in 670 chow-fed Diversity Outbred in Australia (DOz) mice and identified a genome-wide significant locus (QTL) on chromosome 8 encompassing 17 defensin genes. By taking a systems genetics approach, we identified alpha-defensin 26 (Defa26) as the causal gene in this region.
View Article and Find Full Text PDFNat Microbiol
September 2025
Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, NY, USA.
Microbial influence on cancer development and therapeutic response is a growing area of cancer research. Although it is known that microorganisms can colonize certain tissues and contribute to tumour initiation, the use of deep sequencing technologies and computational pipelines has led to reports of multi-kingdom microbial communities in a growing list of cancer types. This has prompted discussions on the role and scope of microbial presence in cancer, while raising the possibility of microbiome-based diagnostic, prognostic and therapeutic tools.
View Article and Find Full Text PDFObes Surg
September 2025
St Vincent's Hospital Sydney, Darlinghurst, Australia.
Background: One-anastomosis gastric bypass (OAGB) has gained popularity as a bariatric operation due to its shorter operation time and lower perioperative complication rates, compared with Roux-en-Y gastric bypass (RYGB). However, OAGB is associated with short and long-term complications. Notably, in some reports a subset of patients developed liver dysfunction after OAGB, in some cases causing death or requiring liver transplantation.
View Article and Find Full Text PDFArch Toxicol
September 2025
Norwegian Scientific Committee for Food and Environment, Norwegian Institute of Public Health, Oslo, Norway.
The transition from traditional animal-based approaches and assessments to New Approach Methodologies (NAMs) marks a scientific revolution in regulatory toxicology, with the potential of enhancing human and environmental protection. However, implementing the effective use of NAMs in regulatory toxicology has proven to be challenging, and so far, efforts to facilitate this change frequently focus on singular technical, psychological or economic inhibitors. This article takes a system-thinking approach to these challenges, a holistic framework for describing interactive relationships between the components of a system of interest.
View Article and Find Full Text PDF