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Purpose: The emphasis on early diagnosis to improve cancer survival has been a key factor in the development of cancer pathways across Europe. The aim of this analysis was to explore how the emphasis on early diagnosis and timely treatment is reflected in patient's accounts of care, from the first suspicion of colorectal or lung cancer to their treatment in Denmark, England and Sweden.
Method: We recruited 155 patients in Denmark, England and Sweden who were within six months of being diagnosed with lung or colorectal cancer. Data were collected via semi-structured narrative interviews and analysed using a thematic approach.
Results: Participants' accounts of quality of care were closely related to how quickly (or not) diagnosis, treatment and/or healthcare processes went. Kinetic metaphors as a description of care (such as treadmill) could be interpreted positively as participants were willing to forgo some degree of control and accept disruption to their lives to ensure more timely care. Drawing on wider cultural expectations of the benefits of diagnosing and treating cancer quickly, some participants were concerned that the waiting times between interventions might allow time for the cancer to grow.
Conclusions: Initiatives emphasising the timeliness of diagnosis and treatment are reflected in the ways some patients experience their care. However, these accounts were open to further contextualisation about what speed of healthcare processes meant for evaluating the quality of their care. Healthcare professionals could therefore be an important patient resource in providing reassurance and support about the timeliness of diagnosis or treatment.
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http://dx.doi.org/10.1016/j.ejon.2018.04.002 | DOI Listing |
Oral Oncol
September 2025
Center for Surgery and Public Health, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital; Center for Head and Neck Oncology, D
Introduction: Delays in head and neck cancer (HNC) diagnosis and treatment and financial burdens of care are often rooted in social determinants of health (SDOH), such as financial instability, socioeconomic status (SES), health insurance status, and transportation barriers. While these factors are well recognized, their underlying impact on access to care remains underexplored; this qualitative study aims to investigate how these SDOH facilitate or hinder HNC care through insights from patients and healthcare workers (HCWs) in the United States, to identify targets for intervention.
Methods: Semi-structured interviews were conducted with patients with newly diagnosed HNC, and HCWs caring for these patients, between June 2022 and July 2023.
Front Microbiol
August 2025
Department of Laboratory Medicine, Qingdao University Affiliated Yantai Yuhuangding Hospital, Yantai, China.
Purpose: To evaluate the performance of targeted next-generation sequencing (tNGS) in pathogen detection in acute lower respiratory infection.
Methods: The retrospective study was conducted between July 2023 and May 2024 at the Yantai Yuhuangding Hospital. Patients with acute lower respiratory infections were included.
Front Public Health
September 2025
ShanX Medtech, Eindhoven, Netherlands.
Practical next generation sequencing (NGS) technologies are entering the high-throughput diagnostic clinical microbiology laboratory. Bacterial whole genome sequences (WGS) can be used for detection and identification of species and their (relative) quantification. Genomic relatedness and epidemiological spread of strains of microorganisms can be traced, in parallel with detection of virulence genes as well as genes involved in antimicrobial resistance (AMR).
View Article and Find Full Text PDFJAMA Pediatr
September 2025
Department of Pediatrics, Nemours Children's Health, Wilmington, Delaware.
Importance: Guidelines for the timely emergency department (ED) administration of opioids for acute sickle cell disease (SCD) pain lack clear evidence showing associations with reduced hospitalizations.
Objective: To evaluate the associations between the timely administration of multiple opioid doses during uncomplicated SCD pain episodes in children and hospitalization.
Design, Setting, And Participants: This multisite cross-sectional study used data from the Pediatric Emergency Care Applied Research Network Registry.
Genet Med
August 2025
Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN USA.
Purpose: Infantile Krabbe disease (IKD) is a severe, progressive neurological disorder that was recently added to the Recommended Uniform Screening Panel in the US. IKD is a critical condition that requires a hematopoietic stem cell transplant (HSCT) preferably by 30 days of age. This study examines if the two-tier newborn screening (NBS) strategy (psychosine (PSY) analysis when enzyme activity is low) causes clinically relevant delays compared with PSY measured at a first clinical follow up visit.
View Article and Find Full Text PDF