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http://dx.doi.org/10.1182/blood-2018-01-825943 | DOI Listing |
Histopathology
August 2024
Guys & Thomas' NHS Foundation Trust, London, UK.
Aims: There have been exceptional reports of morphoea presenting with epidermal changes overlapping histopathologically with cutaneous T cell lymphoma of the mycosis fungoides type (MF). This phenomenon gives rise to an ambiguous clinicopathological scenario in which distinguishing these conditions may be challenging. The aim of this study is to characterise the clinical, histopathological and molecular findings of this phenomenon through a case series.
View Article and Find Full Text PDFAm J Clin Pathol
February 2024
Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, US.
Objectives: Adult T-cell leukemia/lymphoma (ATLL) is a rare aggressive T-cell leukemia/lymphoma associated with human T lymphotropic virus type 1 infection. The patients might present with skin rash before, at, or after the diagnosis. The dermatopathologic finding might be diagnostically very challenging.
View Article and Find Full Text PDFJ Dermatol
May 2019
Department of Dermatology, Kansai Medical University Medical Center, Osaka, Japan.
A 65-year-old Japanese man presented with a dome-shaped nodule, the base of which was contiguous with a dull brown plaque, on the left leg. After local excision of the cutaneous lesion and left inguinal lymph node dissection, several dermal and subcutaneous nodules developed successively on the left lower extremity. Hematoxylin-eosin staining of the primary cutaneous lesion demonstrated uniform neoplastic cells arranged in a trabecular pattern extending from the dermis to subcutis.
View Article and Find Full Text PDFJ Am Acad Dermatol
February 2015
Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York. Electronic address:
Background: Limited data exist regarding cutaneous involvement of adult T-cell leukemia/lymphoma (ATLL), particularly in the United States.
Objective: We sought to characterize clinical and histopathologic features of ATLL in patients with skin involvement.
Methods: We retrospectively identified patients with ATLL from a single institution given a diagnosis during a 15-year period (1998-2013).