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Article Abstract
Optically active cyclopropanes (e.g. 1) can be prepared by the use of tartaric acid derivatives as chiral auxiliaries in the palladium-catalyzed cross-coupling of optically active cyclopropylboronic acids with electrophiles. The absolute configuration of the chiral carbon atom is retained, and the reaction proceeds with good yields and enantiomeric excesses. R=H, p-Ph, o-CO CH , p-CO CH , p-NO , o-OCH , m-OCH .
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| http://dx.doi.org/10.1002/(SICI)1521-3773(19981102)37:20<2845::AID-ANIE2845>3.0.CO;2-U | DOI Listing |
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