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HIV programs have provided a major impetus for investments in surveillance data, with 5-10% of HIV program budgets recommended to support data. However there are questions concerning the sustainability of these investments. The Sustainable Development Goals have consolidated health into one goal and communicable diseases into one target (Target 3.3). Sustainable Development Goals now introduce targets focused specifically on data (Targets 17.18 and 17.19). Data are seen as one of the three systemic issues (in Goal 17) for implementing Sustainable Development Goals, alongside policies and partnerships. This paper reviews the surveillance priorities in the context of the Sustainable Development Goals and highlights the shift from periodic measurement towards sustainable disaggregated, real-time, case, and patient data, which are used routinely to improve programs. Finally, the key directions in developing person-centered monitoring systems are assessed with country examples. The directions contribute to the Sustainable Development Goal focus on people-centered development applied to data.
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http://dx.doi.org/10.2196/publichealth.8173 | DOI Listing |
iScience
September 2025
Department of Physical Geography and Ecosystem Science, Lund University, 223 62 Lund, Sweden.
Forest loss, fragmentation, and transformation negatively impact forest biodiversity and ecosystem functionality worldwide. Improving landscape intactness and connectivity through restoration is critical. Determining where to restore remains, however, a challenge.
View Article and Find Full Text PDFFront Comput Neurosci
August 2025
Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, United States.
Artificial neural networks are limited in the number of patterns that they can store and accurately recall, with capacity constraints arising from factors such as network size, architectural structure, pattern sparsity, and pattern dissimilarity. Exceeding these limits leads to recall errors, eventually leading to catastrophic forgetting, which is a major challenge in continual learning. In this study, we characterize the theoretical maximum memory capacity of single-layer feedforward networks as a function of these parameters.
View Article and Find Full Text PDFJ Pharm Policy Pract
September 2025
Jeffrey Cheah School of Medicine and Health Sciences (JCSMHS), Monash University Malaysia, Bandar Sunway, Malaysia.
Background: Medicine affordability is a critical component of a country's redistributive health policies aimed at ensuring equitable access to healthcare. This study aims to investigate key stakeholders' perspectives on pharmaceutical pricing control in Malaysia as the country is moving towards sustainable healthcare.
Methods: Semi-structured interviews ( = 16) were conducted with a purposive sampling of key stakeholders, which included practitioners and policymakers engaged in Malaysia's public health policy.
MedComm (2020)
September 2025
Immunoglobulin A nephropathy (IgAN), the most prevalent primary glomerulonephritis globally, is characterized by mesangial IgA deposition and heterogeneous clinical trajectories. Historically, management relied on renin-angiotensin system inhibition and empirical immunosuppression, yet high lifetime kidney failure risk persists despite optimized care. This review synthesizes advances in molecular pathogenesis, highlighting how the traditional multi-hit hypothesis-while foundational for targeted therapy development-fails to capture IgAN's recurrent, self-amplifying nature.
View Article and Find Full Text PDFACS Electrochem
September 2025
School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
The study of electrochemical oxidations has wide-ranging implications, from the development of new electrocatalysts for fuel cells for energy conversion, to the synthesis of fine chemicals. 2,2,6,6-Tetramethylpiperidine-1-oxyl (TEMPO) has been used for decades as a sustainable, metal-free mediator for chemical oxidations and is now being used for electrochemical oxidations. We describe here a novel approach to TEMPO-mediated electrooxidations, in which the chemical input and waste generated during electrooxidations of alcohols are minimized by using a multifunctional room temperature ionic liquid (RTIL) to facilitate flow electrosynthesis.
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