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http://dx.doi.org/10.1016/j.jvsv.2018.02.003 | DOI Listing |
Spine Deform
September 2025
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Purpose: A subset of adult spinal deformity (ASD) patients undergoing corrective surgery receive a disproportionate level of medical resources and incur greater costs. We examined the characteristics of such super-utilizers of health care resources among ASD patients.
Methods: This prospective, multicenter study analyzed data from ASD patients with > 4 levels of spinal fusion and a minimum 2-year follow-up.
Respir Med
September 2025
Centre of Excellence in Treatable Traits, College of Health, Medicine and Wellbeing, University of Newcastle, New Lambton Heights, NSW, Australia; Asthma and Breathing Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia; Department of Respiratory and Sleep Medici
Background: The benefits of oral corticosteroid (OCS) stewardship approaches -including monoclonal antibody treatments for severe asthma- on reducing toxic OCS exposure and related comorbidities such as depression and anxiety require real-world evaluation.
Methods: This real-world observational study investigated OCS exposure and associated complications over 24 months in patients enrolled in the Australian Mepolizumab Registry (n = 412).
Results: Patients were median age 59 years, 58 % were female.
Int J Radiat Oncol Biol Phys
September 2025
Department of Radiation Oncology, Saitama Medical Center, Saitama, Japan.
Purpose: Although pain response is assessed based on the intensity of index pain (pain from the tumor targeted for radiation therapy), few studies have explored non-index pain (pain from other sites not targeted for radiation therapy). We examined the impact of pre-treatment non-index pain on quality of life (QOL) after radiation therapy.
Methods And Materials: Of 232 patients enrolled in the original prospective observational study conducted at 26 centers, 223 were analyzed.
Study Question: Can patient age and ovarian reserve tests predict the number of cryopreserved oocytes in patients undergoing one or more ovarian stimulation cycles for elective oocyte cryopreservation (EOC)?
Summary Answer: A predictive model incorporating patient age, antral follicle count (AFC), anti-Müllerian hormone (AMH), and FSH levels achieved the greatest predictive accuracy.
What Is Known Already: As a consequence of societal evolution, women are increasingly delaying starting a family. However, the natural decline in ovarian reserve and oocyte quality as age advances can increase the risk of age-related fertility decline (ARFD) and involuntary childlessness.
Lancet HIV
September 2025
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA; Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, USA. Electronic address:
Background: Past cohort studies have examined mortality among children and young adolescents (aged 0-14 years) who have received antiretroviral therapy (ART), but no systematic reviews have been undertaken to synthesise these findings. Our study aims to provide the most comprehensive global estimates of paediatric mortality among children and adolescents receiving ART.
Methods: For this systematic review and meta-regression analysis, we searched PubMed and Embase from Jan 1, 1990 to July 31, 2024 for studies reporting mortality among children and young adolescents living with HIV who were on ART.