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Humans acquire their most basic physical concepts early in development, and continue to enrich and expand their intuitive physics throughout life as they are exposed to more and varied dynamical environments. We introduce a hierarchical Bayesian framework to explain how people can learn physical parameters at multiple levels. In contrast to previous Bayesian models of theory acquisition (Tenenbaum, Kemp, Griffiths, & Goodman, 2011), we work with more expressive probabilistic program representations suitable for learning the forces and properties that govern how objects interact in dynamic scenes unfolding over time. We compare our model to human learners on a challenging task of estimating multiple physical parameters in novel microworlds given short movies. This task requires people to reason simultaneously about multiple interacting physical laws and properties. People are generally able to learn in this setting and are consistent in their judgments. Yet they also make systematic errors indicative of the approximations people might make in solving this computationally demanding problem with limited computational resources. We propose two approximations that complement the top-down Bayesian approach. One approximation model relies on a more bottom-up feature-based inference scheme. The second approximation combines the strengths of the bottom-up and top-down approaches, by taking the feature-based inference as its point of departure for a search in physical-parameter space.
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http://dx.doi.org/10.1016/j.cogpsych.2017.05.006 | DOI Listing |
Neurochem Res
September 2025
Biology and Health Laboratory, Faculty of Sciences, Ibn Tofail University, Kenitra, Morocco.
Parkinson's disease (PD) is characterized by impairments in motor control following the degeneration of dopamine-producing neurons located in the substantia nigra pars compacta. Environmental pesticides such as Paraquat (PQ) and Maneb (MB) contribute to the onset of PD by inducing oxidative stress (OS). This study evaluated the therapeutic efficacy of moderate physical activity (PA) on both motor and non-motor symptoms in a Wistar rat model of Paraquat and Maneb (PQ/MB) induced PD.
View Article and Find Full Text PDFBull Math Biol
September 2025
Department of Mathematics, Siena University, 515 Loudon Road, Loudonville, NY, 12211, USA.
Autonomous differential equation compartmental models hold broad utility in epidemiology and public health. However, these models typically cannot account explicitly for myriad factors that affect the trajectory of infectious diseases, with seasonal variations in host behavior and environmental conditions as noteworthy examples. Fortunately, using non-autonomous differential equation compartmental models can mitigate some of these deficiencies, as the inclusion of time-varying parameters can account for temporally varying factors.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
October 2025
Niigata Spine Surgery Center, Kameda Daiichi Hospital, Niigata, Japan.
Study Design: Prospective cohort study.
Objective: To investigate longitudinal changes in physical functional status after long corrective fusion in patients with adult spinal deformity (ASD) during 2 years of follow-up.
Background: In ASD surgery, reports assessing physical functional status in long-term observations for more than a year are lacking.
Cancer
September 2025
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Background: The influence of obesity and sex on outcomes in pancreatic adenocarcinoma (PDAC) remains unclear. The association between obesity (body mass index [BMI], ≥30) and biologic sex (male or female) for outcomes in patients with PDAC undergoing a surgery-first approach was investigated.
Methods: A prospectively maintained pancreatic cancer database at the Memorial Sloan Kettering Cancer Center was queried to identify all patients undergoing surgery with a pathologic diagnosis of PDAC.
Sleep
September 2025
Center for Sleep Medicine, Hospices Civils de Lyon, Lyon 1 University, Lyon, F-69000, France.
Current treatments for narcolepsy type 1 (NT1) have little impact on psychiatric, cognitive and metabolic comorbidities. Here, we evaluated the feasibility, safety and efficacy of a prospective Exercise Training (ET) program on sleep-related symptoms and comorbidities in NT1. Sedentary adult with NT1 participated in a 6-week supervised ET program followed by a 18-week self-directed program.
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