98%
921
2 minutes
20
Prognosis has not been known for patients with fever of unknown origin (FUO) whose ¹⁸fluoro-deoxyglucose (¹⁸F-FDG) positron emission tomography/computerized tomography (PET/CT) finding is non-diagnostic. A total of eight patients with FUO that underwent ¹⁸F-FDG PET/CT were retrospectively identified January 2016 - June 2017 in a tertiary hospital in Korea. Of these, two patients were diagnosed with microscopic polyangitis and Kikuchi's disease and one patient was transferred to another hospital. Of five patients whose diagnoses were not confirmed, four patients received non-steroidal anti-inflammatory drug and/or low dose steroid and symptoms disappeared. Our study suggests that outcome of patients with FUO whose ¹⁸F-FDG PET/CT finding is non-diagnostic would be favorable.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895830 | PMC |
http://dx.doi.org/10.3947/ic.2018.50.1.43 | DOI Listing |
Am Surg
September 2025
Medical School, Universidade Federal de Ouro Preto, Ouro Preto, Brazil.
IntroductionThe optimal diagnostic pathway for pediatric acute appendicitis (AA) following an inconclusive or negative ultrasonography (US) is poorly defined, leading to debate over subsequent computed tomography (CT) use. This systematic review and meta-analysis compared negative appendectomy rates in children managed with a US-only pathway vs a pathway involving CT after a non-diagnostic initial US.MethodsFollowing PRISMA guidelines (PROSPERO: CRD42024568560), we systematically searched 6 databases, including PubMed and Embase, through July 2024 for longitudinal studies comparing the 2 diagnostic pathways.
View Article and Find Full Text PDFSleep
September 2025
IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italia.
Study Objectives: For most sleep disorders, in-laboratory video-polysomnography (VPSG) is currently considered the gold diagnostic standard. However, a growing need for more accessible diagnostic tools has been highlighted. This study aims to describe the experience of the Bologna Sleep Center in evaluating sleep-related motor behaviors using home VPSG.
View Article and Find Full Text PDFEur Radiol
September 2025
Department of Radiology & Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Objectives: Reducing motion artifacts in coronary computed tomography angiography (CCTA) is essential for accurate coronary artery disease assessment. We evaluated the clinical performance of a motion-compensated reconstruction (MCR) using subjective image quality (SIQ) and interpretability of CCTA at varying heart rates (HR).
Materials And Methods: We retrospectively identified 150 patients, grouped by HR (≤ 60, 60-69, ≥ 70 bpm, n = 50 each), referred for prospective ECG-gated CCTA on a spectral dual-layer CT.
Cancer Rep (Hoboken)
September 2025
Western Australia Gynaecological Cancer Service, King Edward Memorial Hospital, Subiaco, Western Australia, Australia.
Background: Poly-ADP ribose polymerase inhibitors have been shown to improve progression-free survival in patients with advanced high-grade epithelial non-mucinous ovarian cancers characterized by a deficiency in homologous recombination (HRD). Guidelines recommend all patients with advanced high-grade epithelial ovarian cancer undergo genomic tumor testing for HRD. Our aim was to evaluate the first year of HRD testing at the statewide Western Australia Gynecologic Cancer Service to assess factors associated with obtaining a diagnostic HRD testing result.
View Article and Find Full Text PDFGenes (Basel)
July 2025
Istituto Zooprofilattico Sperimentale del Lazio e della Toscana M. Aleandri, 58100 Grosseto, Italy.
: The gene pool of the Apennine wolf is affected by admixture with domestic variants due to anthropogenic hybridisation with dogs. Genetic monitoring at the population level involves assessing the extent of admixture in single individuals, ranging from pure wolves to recent hybrids or wolf backcrosses, through the analysis of nuclear and mitochondrial DNA (mtDNA) markers. Although individually non-diagnostic, mtDNA is nevertheless essential for completing the final diagnosis of genetic admixture.
View Article and Find Full Text PDF