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http://dx.doi.org/10.1097/MPA.0000000000001012 | DOI Listing |
Mol Imaging Radionucl Ther
September 2025
University Clinical Center of Serbia, Center for Nuclear Medicine with PET, Belgrade, Serbia.
Fluorine-fluorocholine (F-FCH) is a radiopharmaceutical used in primary hyperparathyroidism. The data about its utility in malignancies other than prostate and hepatocellular carcinoma is limited. We present the case of a patient who was referred for F-FCH positron emission tomography/computed tomography (PET/CT) due to the persistently elevated parathormone and calcium levels following total thyroidectomy with left lower parathyroidectomy for parathyroid carcinoma (PTC).
View Article and Find Full Text PDFImaging Neurosci (Camb)
August 2025
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States.
Functional Positron Emission Tomography (fPET) with (bolus plus) constant infusion of [F]-fluorodeoxyglucose (FDG), known as fPET-FDG, is a recently introduced technique in human neuroimaging, enabling the detection of dynamic glucose metabolism changes within a single scan. However, the statistical analysis of fPET-FDG data remains challenging because its signal and noise characteristics differ from both classic bolus-administration FDG PET and from functional Magnetic Resonance Imaging (fMRI), which together compose the primary sources of inspiration for analytical methods used by fPET-FDG researchers. In this study, we present an investigation of how inaccuracies in modeling baseline FDG uptake can introduce artifactual patterns to detrended time-activity curve (TAC) residuals, potentially introducing spurious (de)activations to general linear model (GLM) analyses.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
September 2025
Department of Clinical Medicine, Aarhus University, Denmark.
Context: Alternate day fasting (ADF) is a dietary regimen with prolonged fasting periods associated with metabolic and cardiovascular benefits. It remains unclear if ADF improves cardiac function and metabolism to explain these benefits.
Objective: This study aimed to investigate the effects of a three-week ADF intervention on myocardial efficiency, perfusion, and substrate metabolism in overweight/obese individuals.
Acta Oncol
August 2025
Department of Biomedicine, Aarhus University, Aarhus, Denmark; Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Denmark.
Background And Purpose: Quantification/mapping of tumor hypoxia may guide pretreatment decision-making in radiation oncology. Hypoxia-selective positron emission tomography (PET) tracers, like 18F-fluoroazomycin arabinoside (FAZA), allow assessment of hypoxia, but since hypoxia stimulates glycolysis, fluorodeoxyglucose (FDG) and hypoxia-PET may provide overlapping/similar information. Clinical dual-tracer PET studies are highly complex and remain inconclusive.
View Article and Find Full Text PDFNucl Med Commun
August 2025
Research Institute, Fundación Universitaria de Ciencias de la Salud (FUCS).
Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disorder that frequently presents as fever of unknown origin (FUO), posing a diagnostic challenge. This study aimed to systematically review the diagnostic utility of 18F-labeled fluorodeoxyglucose (18F-FDG) PET/computed tomography (CT) in AOSD. A systematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and registered in PROSPERO (CRD42023443831).
View Article and Find Full Text PDF