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Objective: To investigate the computer-assisted virtual reduction combined with 3D printing technique as preoperative planning and assess their therapeutic effects.
Methods: Thirty-five cases of acetabular fracture treated by internal fixation from March 2011 and March 2014 were retrospectively analyzed. All patients underwent operations with internal fixations implanted. The patients were divided into 2 groups according whether they used the computer-assisted virtual reduction combined with 3D printing technology. Fifteen patients in the digital group included 9 males and 6 females with a mean age of (39.4±8.8) years old ranging from 22 to 58 years old;time from injury to the operation was (8.8±2.0) days;for Letournel-Judet classification, 4 cases were both column fracture, 5 cases were posterior wall fracture, 4 cases were T-fracture, 2 cases were posterior wall with transverse fracture. Twenty cases in the control group included 12 males and 8 females with a mean age of (38.7±13.1) years old ranging from 19 to 59 years old;time from injury to the operation was(8.2±2.3) days;for Letournel-Judet classification, 6 cases were both column fracture, 8 cases were posterior wall fracture, 3 cases were T-fracture, 3 cases were posterior wall with transverse fracture. The volume of intraoperative blood loss and blood transfusion, operative time, satisfaction rate of fracture reduction and excellent and good rate of d`Aubigne Postal function evaluation were compared between the two groups and statistical analysis was conducted.
Results: All the incisions healed without infection occurred. All the fractures healed without breakage or loosening of plates and screws. There was 1 case of postoperative nerve stimulation symptoms in each group. One patient in the digital group was found necrosis of the femoral head at 6 months after operation. One patient in the control group was found heterotopic ossification at 8 months after operation. All patients were follow-up for 13 to 28 months with an average of 17.6 months. The volume of intraoperative blood loss and blood transfusion in the digital group were significantly less than those in the control group(<0.05). The operation time in the digital group was shorter than that in the control group(<0.05). The excellent and good rates of fracture reduction were 92.9%(14/15) and 85%(17/20) in the digital group and the control group respectively, and there was no statistical significance (>0.05). The excellent and good rates of Aubigne Postal function evaluation were 86.7%(13/15) and 80%(16/20) respectively, and there was no significant difference(>0.05).
Conclusions: The computer-assisted virtual reduction combined with 3D printing technique can reduce the operative time, volume of intraoperative blood loss and blood transfusion in acetabular surgeries for patients with acetabular fractures. The technique is an effective method for preoperative planning, which worth promoting.
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http://dx.doi.org/10.3969/j.issn.1003-0034.2017.07.009 | DOI Listing |
J Appl Clin Med Phys
September 2025
Clinical Imaging Physics Group, Duke University Health System, Durham, North Carolina, USA.
Introduction: Medical physicists play a critical role in ensuring image quality and patient safety, but their routine evaluations are limited in scope and frequency compared to the breadth of clinical imaging practices. An electronic radiologist feedback system can augment medical physics oversight for quality improvement. This work presents a novel quality feedback system integrated into the Epic electronic medical record (EMR) at a university hospital system, designed to facilitate feedback from radiologists to medical physicists and technologist leaders.
View Article and Find Full Text PDFClin Implant Dent Relat Res
October 2025
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Introduction: This in vitro study evaluated how different forces applied to the dental drill handle during static computer-assisted implant surgery influence surgical guide deformation and implant placement accuracy.
Methods: Twenty-four virtual implants were divided into six groups (0-10 N, in 2 N increments). Surgical guides were scanned under loaded conditions, and deviations were quantified by superimposition with the baseline model.
Bioorg Med Chem
September 2025
Goel Institute of Pharmacy and Sciences, Lucknow, Uttar Pradesh 226028, India. Electronic address:
N-methyl-d-aspartate (NMDA) receptors are validated druggable targets for the treatment of Alzheimer's and other associated neurological conditions, particularly in individuals with disabilities. Considering the excitotoxicity associated with NMDA receptors, which leads to neuronal damage, cognitive impairment, and limitations of current therapeutic regimens, better therapeutic candidates are required. One of the validated drug discovery approaches is computer-assisted drug discovery, supplemented by molecular docking, mechanics, and dynamics.
View Article and Find Full Text PDFActa Oncol
September 2025
Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
Background And Purpose: Photon-counting computed tomography (PCCT) offers enhanced image quality, including improvements in contrast, spatial resolution, and noise reduction. In radiotherapy (RT), optimal image quality is critical for accurate tumor and organ-at-risk delineation. However, reconstruction parameter selection often relies on subjective assessment.
View Article and Find Full Text PDFActa Oncol
September 2025
Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
Background And Purpose: Accurate stopping-power ratio (SPR) estimation is crucial for proton therapy planning. In brain cancer patients with metal clips, SPR accuracy may be affected by high-density materials and imaging artefacts. Dual-energy CT (DECT)-based methods have been shown to improve SPR accuracy.
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