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Objective: Deep NREM sleep and its hallmark EEG phenomenon slow wave activity (SWA) are under homeostatic control in adults. SWA is also locally regulated as it increases in the brain areas that have been used intensively. Moreover, in children, SWA is a marker of cortical maturation. In the present study the local properties of NREM sleep depth were evaluated using the quantitative mean frequency method. We aimed to study if age is related to NREM sleep depth in young infants. In addition, we studied if young infants have local differences in their NREM sleep.
Methods: Ambulatory over-night polysomnographies were recorded in 59 healthy and full-term infants at the age of one month. The infants were divided into two age groups (<44 weeks and ≥44 weeks) to allow maturational evaluations.
Results: The quantitative sleep depth analysis showed differences between the age groups. In addition, there were local sleep depth differences within the age groups.
Conclusions: The sleep depth change with age is most likely related to cortical maturation, whereas the local sleep depth gradients might also reflect the use-dependent properties of SWA.
Significance: The results support the idea that young infants have frontal cortical processing.
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http://dx.doi.org/10.1016/j.clinph.2017.09.116 | DOI Listing |
J Am Coll Health
September 2025
Hubbard School of Journalism and Mass Communication, University of Minnesota, Minneapolis, Minnesota, USA.
: An evolving THC product marketplace is diffusing through college campuses. It is essential to understand college students' THC knowledge, attitudes, practices and product packaging perceptions to identify campus health education and messaging strategies. : Participants were 30 undergraduate college students at a large-midwestern, public university.
View Article and Find Full Text PDFNat Sci Sleep
September 2025
Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
Aim: Obstructive sleep apnea (OSA) is characterized by repetitive upper airway collapse during sleep, resulting in frequent cortical arousals. However, currently used frequency-based arousal metrics do not sufficiently capture the heterogeneity and clinical significance of arousal responses. The odds ratio product (ORP) is a novel electroencephalographic marker that provides a continuous assessment of sleep depth and has the potential to serve as an objective measure of arousal intensity.
View Article and Find Full Text PDFInt J Psychol
October 2025
Department of Psychology "Renzo Canestrari", University of Bologna, Bologna, Italy.
Chronotype is the preference for sleep and activity timing, differentiating individuals into morning (i.e., waking and sleeping early), evening (i.
View Article and Find Full Text PDFNeurology
October 2025
Montreal Neurological Institute-Hospital, McGill University, Montreal, Canada.
Background And Objectives: Years before diagnosis of Parkinson disease (PD), dementia with Lewy bodies (DLB), or multiple system atrophy (MSA), mild prodromal manifestations can be detected. Longitudinal follow-up of people with prodromal synucleinopathy, particularly idiopathic/isolated REM sleep behavior disorder (iRBD), enables in-depth clinical phenotyping of early disease, which could facilitate stratification for clinical trials, provide the definition of appropriate end points, or predict phenoconversion more precisely. The aim of this study was to update and expand on previous studies assessing clinical evolution from iRBD to clinically diagnosed disease, up to 14 years before diagnosis.
View Article and Find Full Text PDFBrain Topogr
September 2025
School of Biomedical Sciences, University of New South Wales (UNSW), Wallace Wurth Building, Kensington, NSW, 2052, Australia.
Different levels of reduced consciousness characterise human sleep stages at the behavioural level. On electroencephalography (EEG), the identification of sleep stages predominantly relies on localised oscillatory power within distinct frequency bands. Several theoretical frameworks converge on the central significance of long-range information sharing in maintaining consciousness, which experimentally manifests as high functional connectivity (FC) between distant brain regions.
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