98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725409 | PMC |
http://dx.doi.org/10.3389/fonc.2017.00302 | DOI Listing |
Front Oncol
December 2017
Cell Death Research and Therapy (CDRT) Lab, Department of Cellular Molecular Medicine, KU Leuven University of Leuven, Leuven, Belgium.
J Am Soc Nephrol
November 2013
Life Sciences Institute, Department of Molecular and Integrative Physiology, Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Autophagy, a cellular process of "self-eating" by which intracellular components are degraded within the lysosome, is an evolutionarily conserved response to various stresses. Autophagy is associated with numerous patho-physiological conditions, and dysregulation of autophagy contributes to the pathogenesis of a variety of human diseases including cancer. Depending on context, activation of autophagy may promote either cell survival or death, two major events that determine pathological process of many illnesses.
View Article and Find Full Text PDF