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Objective: Effective use of state prescription drug monitoring programs (PDMPs) to track controlled substance prescribing and dispensing may help mitigate the current opioid crisis. Our objective was to examine trends in registration for and use of Florida's PDMP by physicians and pharmacists, from 2013 to 2016. We discuss implications for PDMP uptake and policy.
Design: Key measures, such as cumulative number of registrants per license type and monthly utilization intensity, are presented. A time series forecasting approach was used to (1) model the monthly count of new PDMP registrants and users from January 2013 to December 2016 and (2) estimate cumulative registration totals after 1 year.
Setting: Florida.
Results: As of November 2016, there were 16,498 physicians (representing 31 percent of Drug Enforcement Administration licensees) and 17,241 pharmacists registered with the PDMP, representing 21 and 57 percent of professional licensees, respectively. Of note, the PDMP's designation as a "specialized registry" for electronic medical record "meaningful use" criteria led to a nearly sevenfold increase in physician registrations in a single month. In November 2016, pharmacists displayed a higher past-month PDMP utilization rate (52.2 percent vs 30.1 percent), while physicians displayed a higher past-month PDMP utilization intensity (58.1 vs. 36.1 queries per user). Approximately 25,000 physicians and 31,000 pharmacists must register by the end of 2017 to meet national policy goals.
Conclusion: PDMP registration among physicians and pharmacists is limited, and the use of the PDMP among registrants is more limited still. Our findings suggest that Florida will not meet national policy goals for registrants by the end of 2017, although new initiatives may alter this trend. Allowing the PDMP to help prescribers meet other professional needs, such as "meaningful use" or similar efforts, may be effective in increasing PDMP use.
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http://dx.doi.org/10.5055/jom.2017.0397 | DOI Listing |
ACS Nano
September 2025
Catalonia Institute for Energy Research (IREC), Sant Adrià de Besòs, Barcelona 08930, Spain.
Engineering lattice strain, electronic structure, and crystallinity in palladium alloys offers a promising approach to significantly enhance their electrocatalytic performance. In this work, we present a versatile strategy to synthesize Pd-based phosphide alloys integrated with non-noble metal atoms (Pd-M-P; M = Co, Ni, Cu), characterized by expanded lattice structures and a crystalline-amorphous core-shell architecture. Catalytic performance assessments revealed that CuPdP exhibits an impressive mass activity of 7.
View Article and Find Full Text PDFJ Gen Intern Med
July 2025
Center for Healthcare Policy and Research, UC Davis, Sacramento, CA, USA.
Background: Opioid and benzodiazepine co-prescription is associated with overdose, particularly among patients prescribed long-term opioids.
Objectives: Identify predictors of incident benzodiazepine and opioid co-prescription using two separate and complementary large-scale patient cohorts.
Design: Two retrospective cohort studies: (a) statewide dataset based on California's prescription drug monitoring program (PDMP, 7/1/2016-12/1/2018) and (b) national sample of commercial and Medicare Advantage enrollees from the Optum Labs Data Warehouse (OLDW, 7/1/2016-12/1/2021).
Subst Use Misuse
July 2025
Rocky Mountain Poison and Drug Safety, Denver Health and Hospital Authority, Denver, Colorado, USA.
Aims: Gabapentin is not a federally controlled substance, yet multiple states have implemented gabapentin-specific policies in response to non-medical use (NMU). This study aims to compare prevalence of gabapentin NMU by state policy type and examine the association between gabapentin NMU and gabapentin-related state policy types.
Methods: Data come from the Survey of Non-Medical Use of Prescription Drugs, which employed an online cross-sectional survey in the U.
Biologicals
August 2025
International Plasma and Fractionation Association, Plesmanlaan 125, 1066 CX, Amsterdam, the Netherlands. Electronic address:
Edwin Cohn, appointed to the Harvard Medical School in 1920, was commissioned by the United States military in 1940 to develop a stable albumin solution to treat blood/plasma loss from battlefield injury. Albumin was first produced at the Harvard pilot plant using Cohn's five variable, ethanol precipitation process which was rapidly transferred to private industry for industrial manufacture. For the past decades IgG has been used to treat multiple conditions and has become the industry driver whilst albumin is now a low-price commodity.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
July 2025
School of Civil and Environmental Engineering, Cornell University, Ithaca, NY 14853.
Antagonistic interactions are critical determinants of microbial community stability and composition, offering host benefits such as pathogen protection and providing avenues for antimicrobial control. While the ability to eliminate competitors confers an advantage to antagonistic microbes, it often incurs a fitness cost. Consequently, many microbes only produce toxins or engage in antagonistic behavior in response to specific cues like quorum sensing molecules or environmental stress.
View Article and Find Full Text PDF