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Objective: To analyze the associations between fixed-term employment and health (work ability and mental health) and behaviors (engagement and performance). Psychological contract fulfilment (PCF) and breach (PCB) are investigated as potential mediators of these associations.
Methods: Seven hundred workers employed on fixed-term contracts from a broad range of organizations participated in the study. The Structural Equation Model was performed to analyze the data.
Results: Mediation analyses revealed that good physical and mental health and productivity are more likely to be achieved by those workers who perform non-manual work and (to some extent) accept their contracts because they experience high levels of PCF and low levels of PCB.
Conclusions: Apart from the lack of physical workload, psychological contract fulfilment has been revealed as yet another significant mediator between a higher socioeconomic position and good health and productivity of fixed-term workers.
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http://dx.doi.org/10.1097/JOM.0000000000001226 | DOI Listing |
Nurs Rep
June 2025
Faculty of Health Sciences-HM Hospitals, University Camilo José Cela, Urb. Villafranca del Castillo, 49, Villanueva de la Cañada, 28692 Madrid, Spain.
Employment instability is increasingly recognized as an organizational stressor, yet its combined effect on nurse burnout, humanized care, and work engagement is poorly quantified. This study investigates those relationships and tests a serial mediation model linking contract instability, burnout, humanization, and engagement in Spanish hospital nurses. A nationwide cross-sectional survey was completed by 400 fixed-term nurses between March and May 2025.
View Article and Find Full Text PDFNeurotoxicol Teratol
August 2025
Centre de recherche du Centre Hospitalier Universitaire de Sherbrooke, 3001, 12th Avenue North, Sherbrooke (Quebec) J1H 5N4, Canada; Université de Sherbrooke, Department of Pharmacology-Physiology, 3001, 12th Avenue North, Sherbrooke (Quebec) J1H 5N4, Canada. Electronic address: denis.gris@usherbro
The safety of antenatal corticosteroid administration during the late preterm period is currently questioned. This experimental study conducted in a CD-1 mouse model aimed to determine if exposure to betamethasone in the late preterm period 1) induces behavioral changes in adulthood and 2) alters cerebral anatomy. In the prenatal group, four gravid mice were randomly assigned to receive 0.
View Article and Find Full Text PDFLancet Reg Health Eur
June 2025
Department of Paediatric Infectious Diseases & Immunology, Evelina London Children's Hospital, Guy's & St. Thomas' NHS Foundation Trust, London, United Kingdom.
Background: According to estimates, globally more than 200,000 pregnant women develop tuberculosis (TB) annually. Despite this, data on perinatal TB remain scarce. This study aimed to describe perinatal TB, comprising congenital (cTB) and postnatal (pTB) TB, in a European setting.
View Article and Find Full Text PDFJ Prev Alzheimers Dis
March 2025
University of Southern California, Los Angeles, CA, USA. Electronic address:
Background: The number of people with dementia is expected to grow substantially across the world due to population aging, but cognitive impairment remains undetected and undiagnosed, especially in early stages. Newly available diagnostic tools such as digital cognitive assessments and blood biomarker tests may be well suited to increase the rates of early detection of dementia in primary care.
Objectives: The objective of the Davos Alzheimer's Collaborative Healthcare System Preparedness (DAC-SP) Early Detection Flagship Program was to improve the rate of early detection of cognitive impairment in primary care and non-specialty settings.
Lancet HIV
March 2025
MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK; Department of Paediatric Infectious Diseases, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Background: ODYSSEY showed superior efficacy for dolutegravir-based antiretroviral therapy (ART) versus standard of care (SOC) in children living with HIV starting first-line or second-line ART aged 4 weeks or older. Here, we aim to compare virological outcomes and resistance in the dolutegravir group versus SOC for first-line and second-line ART up to 96 weeks.
Methods: ODYSSEY was an open-label, multicentre, randomised, non-inferiority trial done in 29 centres in seven countries (Germany, Spain, South Africa, Thailand, the UK, Uganda, and Zimbabwe).