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Background: Naming difficulties have recently garnered more interest in elderly individuals with mild cognitive impairment (MCI). We anticipate that naming tests with the consideration of response time can provide more informative and distinct neuropsychological profiles of individuals with MCI.
Methods: Naming tests were administered to 76 elderly individuals with MCI and 149 healthy elderly (HE). We analyzed the impact of MCI on naming performance and occurrence of "delayed" response. We also validated the predictive power of naming tests with a time-constrained scoring system.
Results: MCI participants performed poorer on the noun naming test than HE participants (p = 0.014). MCI was significantly associated with the occurrence of "delayed" response on the noun (odds ratio [OR] = 3.57; 95% confidence interval [CI] = 1.78-7.17) and verb naming tests (OR = 4.66; 95% CI = 2.07-10.46). The time-constrained naming scores were significantly better able to distinguish the MCI from the HE group than the conventional spontaneous naming score on both the noun (p < 0.001) and verb (p = 0.002) naming tests.
Conclusions: Our findings broaden the knowledge related to the naming ability in individuals with MCI, with respect to the response time. We also confirmed the validity of the naming tests by applying the "delayed" responses as supplementary assessments in the diagnosis of MCI.
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http://dx.doi.org/10.1159/000479149 | DOI Listing |
PLoS One
September 2025
NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and Institute of Ophthalmology University College London, London, United Kingdom.
Objectives: To describe the research principles and cohort characteristics of the multi-disciplinary Project HERCULES, an innovative model of safe high-volume outpatient eye-care service for patients with stable chronic eye diseases. Results and analyses of the workstreams within Project HERCULES will be reported elsewhere. The rationale was to improve eye-care capacity in the National Health Service (NHS) in England through the creation of technician-delivered monitoring in a large retail-unit in a London shopping-centre, with remote asynchronous review of results by clinicians (named Eye-Testing and Review through Asynchronous Clinic (Eye-TRAC)).
View Article and Find Full Text PDFFront Genet
August 2025
Federal Medical and Biologicl Agency, Moscow, Russia.
Background: Familial hypercholesterolemia (FH) is a prevalent hereditary disorder, with its monogenic form linked to an elevated risk of early-onset ischemic heart disease. Evaluating the prevalence and penetrance of pathogenic and likely pathogenic variants associated with this disorder would provide valuable information supporting routine FH screening of the general population. Such informed screening would facilitate early identification of at-risk individuals, enabling timely intervention and management.
View Article and Find Full Text PDFFollowing a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of the fungal biomass from species strain as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF as the frozen form of the sp. str.
View Article and Find Full Text PDFJ Colloid Interface Sci
August 2025
School of Chemistry, Dalian University of Technology, Dalian 116024, PR China; College of Environment and Chemical Engineering, Dalian University, Dalian 116622, China. Electronic address:
Aqueous batteries have become a prospective future energy storage system because of their low coefficient of cost and stability. However, their lower energy density limits their applications. Ammonium ions (NH) have a small hydration radius and light molar mass, and aqueous ammonium ion batteries (AAIBs) are anticipated for solving the inherent low-energy density problem of aqueous batteries.
View Article and Find Full Text PDFPsychother Psychosom
September 2025
Division of Endocrinology and Diabetology, Department of Internal Medicine, Interdisciplinary Metabolic Medicine Trials Unit, Medical University of Graz, Graz, Austria.
Introduction: Understanding chronic stress as a potential risk factor for COVID-19 progression could inform public health measures and personalized preventive interventions. Therefore, we investigated the influence of chronic stress prior to SARS-CoV-2 infection on symptom persistence 1 month after COVID-19 onset.
Methods: The participants of this prospective cohort study named "StressLoC" were adults with COVID-19 who had tested positive for SARS-CoV-2 infection within the last 7 days.