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Abnormally high deposition of iron can contribute to neurodegenerative disorders with cognitive impairment. Since previous studies investigating cognition-brain iron accumulation relationships focused on elderly people, our aim was to explore the association between iron concentration in subcortical nuclei and two types of memory performances in a healthy young population. Gender difference was found only in the globus pallidus. Our results showed that iron load characterized by R2* value on the MRI in the caudate and putamen was related to visual memory, while verbal memory was unrelated to iron concentration.
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http://dx.doi.org/10.3233/JAD-170118 | DOI Listing |
Anal Methods
September 2025
Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin 541004, China.
A novel magnetic nanostructured molecularly imprinted polymer probe (FeO@MIP) was developed for the continuous detection of Ti/Fe. The synthesis employed 50 nm FeO nanoparticles as the core matrix, with Ti and Fe serving as template molecules. Functional monomers α-methylacrylic acid (MAA) and acrylamide (AM) were used, along with ethylene glycol dimethacrylate (EGDMA) as the crosslinking agent and 2,2'-azobisisobutyronitrile (AIBN) as the polymerization initiator, utilizing a microwave-assisted procedure.
View Article and Find Full Text PDFBiochim Biophys Acta Biomembr
September 2025
Laboratório de Bioquímica Celular, Universidade Federal de São João del Rei, Campus Centro-Oeste Dona Lindu, Divinópolis, MG, Brazil. Electronic address:
Lactoferrin (Lf) is an iron-binding glycoprotein involved in various biological functions, including iron metabolism and immune response. Bovine lactoferrin (bLf) has gained attention due to its potential therapeutic applications. This study investigates the effects of bLf on human erythrocyte membranes, focusing on Na,K-ATPase (NKA) modulation.
View Article and Find Full Text PDFComput Methods Programs Biomed
September 2025
Department of Medical Imaging and Radiation Sciences, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Australia. Electronic address:
Background And Purpose: Several studies have shown changes in neurochemicals within the deep-brain nuclei of patients with psychosis. These alterations indicate a dysfunction in dopamine within subcortical regions affected by fluctuations in iron concentrations. Quantitative Susceptibility Mapping (QSM) is a method employed to measure iron concentration, offering a potential means to identify dopamine dysfunction in these subcortical areas.
View Article and Find Full Text PDFJ Environ Manage
September 2025
College of Resources, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Investigation and Monitoring, Protection and Utilization for Cultivated Land Resources, Ministry of Natural Resources, Chengdu, 611130, China. Electronic address:
While organic manure application effectively increases soil organic carbon (SOC) content, it may elevate greenhouse gas emissions. Crop straw, a widely available agricultural residue, enhances SOC through gradual decomposition. The effect of organic manure combined with crop straw on the organic carbon components of paddy soil is still unclear.
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