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http://dx.doi.org/10.4103/sni.sni_17_17 | DOI Listing |
J Neurooncol
September 2025
Department of Radiotherapy and Radiation Oncology, Philipps- Universität Marburg, Marburg, Germany.
Background: Pituitary adenomas are relatively common benign intracranial tumors that may cause significant hormonal imbalances and visual impairments. Radiotherapy (RT) remains an important treatment option, particularly for patients with residual tumor after surgery, recurrent disease, or ongoing hormonal hypersecretion. This study summarizes long-term clinical outcomes and radiation-associated toxicities in patients with pituitary adenomas treated with contemporary radiotherapy techniques at a single institution.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
September 2025
Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland.
Isolated ectopic secretion of corticotropin-releasing hormone (CRH) is an exceedingly rare cause of Cushing's syndrome (CS), accounting for fewer than 1% of cases. Ectopic CS is an uncommon but potentially life-threatening condition that often necessitates urgent diagnostic evaluation and treatment. Hormonal testing may suggest a pituitary origin, complicating the diagnostic process.
View Article and Find Full Text PDFEndocr Connect
September 2025
Centre for Higher Education Development, University of Cape Town.
Background: Cortisol and growth hormone are important for sleep regulation and cognition. Sleep is critical for cognitive functioning, and memory consolidation. Patients with pituitary disease experience hormonal dysregulation, impaired sleep quality, and cognitive dysfunction.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
September 2025
Endocrinology & Nutrition Department, Hospital Universitario de Vall d´Hebron, Barcelona, Spain.
Objective: Pituitary adenomas (PAs) are one of the three major lesions in Multiple Endocrine Neoplasia type 1 (MEN1), with a prevalence of 32 to 58%, yet their specific risk factors remain unidentified. This study aimed to identify predictors influencing PA occurrence in MEN1.
Methods: This nationwide, multicenter, retrospective cohort study involved 240 MEN1 patients, 55.
Pituitary
September 2025
Facoltà Di Medicina E Chirurgia, Università Cattolica del Sacro Cuore, Rome, Italy.
Introduction: Pituitary adenomas (PAs) are generally benign neoplasms, though in rare cases may exhibit aggressive behavior. In 2024, the PANOMEN-3 workshop released a new clinical-pathological classification. The objective of this study was to examine the potential of the PANOMEN-3 classification to predict prognosis of PAs and guide treatment in our single center cohort of patients with PAs.
View Article and Find Full Text PDF