98%
921
2 minutes
20
Attempts at reconstruction of posttraumatic craniofacial defects (PTCDs) can be a challenge in low-resource practice areas of the world where the needed biomaterials are logistically beyond reach. A simple low-profile technique of autologous osteosynthesis for PTCD using the titanium clamps is presented in this report. In addition, a 6-year prospective database on a consecutive cohort of patients who underwent this procedure was analyzed for clinical, functional, and aesthetic outcomes, both in-hospital and at midterm follow-up. The clinical data of 18 patients, all males, mean age 31.3 years (standard deviation, 9.7), were analyzed. Road traffic accidents (RTAs) were the cause of trauma in 14 of 18 patients (78%) and motorcycle crash, none helmeted, in 10 of the 18 patients (71% of RTAs). Out of 18 cases, 17 were open fractures; 89% suffered mild head injury, and associated brain injury on CT scan included pneumocephalus in 6 (5 of them significant); acute extradural hematoma in 4 and subdural in 2, and brain contusions in 9. The surgery was successful in all the cases: operative time <3 hours in 10 cases (56%), the in-hospital outcome was good in 95%. The median follow-up time was 24 months, in 6 of the 18 cases for ≥36 months. There was no case of surgical site infection in the perioperative or the follow-up period to date. The aesthetic outcome was also acceptable. This surgical technique for the reconstruction of PTCD appears effectual. Although its low cost makes it very attractive therein, it appears to be actually also recommendable even outside the low-resource developing countries.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305308 | PMC |
http://dx.doi.org/10.1055/s-0036-1592096 | DOI Listing |
J Cardiothorac Surg
August 2025
Department of Cardiothoracic Surgery, Aberdeen Royal Infirmary, Aberdeen, UK, AB25 2ZN, United Kingdom.
Background: In the era of minimally invasive valve surgery (MIVS), automated titanium fasteners such as Cor Knot®, have reduced aortic-cross clamp (AXC) and cardiopulmonary bypass (CPB) times to improve survival outcomes. Whilst, most comparative studies pertain to MIVS, there is a lack of literature comparing Cor-Knot (CT) and manual knot tying (MT) in open valve procedures performed via full median sternotomy, particularly the long-term outcomes. We primarily compare AXC and CPB times, residual valvular regurgitation (RVR), freedom from valve re-intervention (FFI) and secondary post-operative outcomes of CT vs MT.
View Article and Find Full Text PDFLife Sci
July 2025
Centro de Investigaciones Cardiovasculares "Dr. Horacio E. Cingolani" (CIC), Facultad de Ciencias Médicas, Universidad Nacional de La Plata-CONICET, La Plata, Buenos Aires, Argentina. Electronic address:
Background: Maladaptive cardiac hypertrophy (MCH) is a pathology that can arise from different diseases, such as arterial hypertension, diabetes, coronary injuries, among others. A candidate for the prevention of MCH is the G protein-coupled estrogen receptor (GPER). It has been determined that the selective activation of this receptor by its synthetic agonist G1 in cardiac tissue prevents and regresses MCH.
View Article and Find Full Text PDFJ Orthop Case Rep
July 2025
Department of Orthopaedics, AIIMS Raipur, Tatibandh, Raipur, Chhattisgarh, India.
Introduction: Isolated quadrilateral plate fracture with central hip dislocation is a rare occurrence. Such difficult-to-treat fractures can be managed with both open reduction and internal fixation (ORIF) and total hip arthroplasty (THA). We hereby describe the management of such a case of neglected irreducible central hip dislocation with quadrilateral plate fracture with THA in this case report.
View Article and Find Full Text PDFInhalation of ultrafine particles (UFP) mediates systemic vascular impairment which is, in part, driven by elevated rates of oxidant generation. One significant source of oxidant production in the vascular compartment is the purine catabolizing enzyme, xanthine oxidoreductase (XOR). However, mechanisms linking XOR and/or endothelial glycosaminoglycan (GAG)-sequestered XOR to vessel dysfunction allied to UFP inhalation remain underexplored.
View Article and Find Full Text PDFFront Oncol
May 2025
Science and Education Division, Public Health Clinical Center of Chengdu, Chengdu, Sichuan, China.
The three patients with AIDS were all male, aged between 56 and 67 years. One also had liver cirrhosis. They presented to the Chengdu Public Health Clinical Medical Center with a history of several months of blood in the stool.
View Article and Find Full Text PDF