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Article Abstract
Replication-dependent double-strand breaks (DSBs) are the main source of genomic instability as their inaccurate repair stimulates chromosomal rearrangements. In a recent work, we uncover a novel regulatory circuit that involves the Werner's syndrome helicase and CDK1, and that is essential for repair pathway choice at replication-dependent DSBs.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286962 | PMC |
| http://dx.doi.org/10.1080/23723556.2016.1268243 | DOI Listing |
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