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Iatrogenic ventriculitis is a potential complication of ventriculostomy drain placement. In this study, an alcohol-impregnated external ventricular drain port cap was added to a standardized ventriculostomy placement bundle. Rates of ventriculitis were reduced postintervention, but this finding did not reach statistical significance.
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http://dx.doi.org/10.1016/j.ajic.2016.06.042 | DOI Listing |
Cureus
January 2025
Department of Neurology, National Hospital Organization Disaster Medical Center, Tokyo, JPN.
Ventriculitis commonly arises as a complication of various central nervous system conditions. The causes of ventriculitis include both iatrogenic conditions, such as catheter-related infections, and non-iatrogenic conditions, such as community-acquired bacterial meningitis. The incidence of pyogenic ventriculitis associated with community-acquired bacterial meningitis remains unclear.
View Article and Find Full Text PDFNeurosurgery
March 2025
Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo , New York , USA.
Background And Objectives: Cerebral ventriculitis remains a challenging neurosurgical condition because of poor outcomes including mortality rates of nearly 80% and a prolonged course of treatment in survivors. Despite current conventional management, outcomes in some cases remain unsatisfactory, with no definitive therapeutic guidelines. This feasibility study aims to explore the use of a novel active, continuous irrigation and drainage system (IRRA flow [IRRAS AB]) combined with intraventricular drug delivery for patients with cerebral ventriculitis.
View Article and Find Full Text PDFWorld Neurosurg
April 2024
Division of Neurosurgery, Maria Cecilia Hospital-GVM Care & Research, Cotignola, Italy.
Radiol Case Rep
May 2021
Department of Neurosurgery, Trauma and Burns Center, Ben Arous, Tunisia.
Gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) is the main contrast agent used in MRI, known for its good tolerance and rare toxicity. Even intrathecal injection of limited doses of Gadolinium can be performed in some indications. To our knowledge, only 3cases of accidental intraventricular injection of Gadolinium have been yet reported in the literature.
View Article and Find Full Text PDFHematol Oncol
April 2021
Department of Neurology, Knappschaftskrankenhaus University of Bochum, Bochum, Germany.
The implantation of a subgaleal reservoir intracerebroventricular (ICV port) in order to apply ICV chemotherapy in patients with leptomeningeal cancer may be complicated by misplacement of the device, pericatheter leucencephalopathy, hemorrhage and iatrogenic ventriculitis/meningitis. Here we analyzed the occurrence of such complications in patients with primary central nervous system lymphoma (PCNSL) treated with systemic and ICV methotrexate- and cytarabine-based chemotherapy. We retrospectively reviewed the medical records of 94 consecutive patients (1247 installations), who had received an ICV port for intraventricular chemotherapy for treatment of histologically confirmed PCNSL at our institution between September 2005 and October 2018.
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