98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.marpolbul.2016.08.040 | DOI Listing |
Biochem Biophys Res Commun
September 2025
Department of Biotechnology & Bioinformatics, Jaypee University of Information Technology, Waknaghat, Solan, H.P., 173234, India. Electronic address:
Abiotic challenges have a major impact on plant growth and development. Recent research has highlighted the role of long non-coding RNAs in response to these environmental stressors. Long non-coding RNAs are transcripts that are usually longer than 200 nucleotides with no potential for coding proteins.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
August 2025
Vatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles; Goodman Luskin Microbiome Center, University of California, Los Angeles; G. Oppenheimer Center for Neurobiology of Stress and Resilience, University of California, Los Angeles; David Geffen School of Me
Background: Despite significant advances in the understanding of the pathogenesis of obesity and influencing factors, its prevalence continues to increase at an alarming rate. Social determinants of health (SDOH) encompass a broad range of psychosocial and environmental factors, including economic stability, education, access to healthcare, social support, isolation, neighborhood disadvantage, discrimination, early life adversity, and stress, all of which have been recognized to significantly increase the risk of obesity.
Aim: This review aims to elucidate the intricate relationship between SDOH and biological mechanisms related to the brain-gut-microbiome (BGM) system that lead to altered eating behaviors and obesity.
Trends Ecol Evol
September 2025
GEOMAR Helmholtz Centre for Ocean Research Kiel, Marine Evolutionary Ecology, Kiel, Germany.
Chromosomal inversions are ubiquitous across the Tree of Life, with genome-wide studies revealing a bias toward smaller inversions, yet research has disproportionately focused on large, supergene-like inversions linked to discrete phenotypes. This limits our understanding of inversions' roles in trait evolution, as their size affects their potential functional impact. Investigation of smaller inversions and multi-inversion genotypes is crucial to elucidate their role in shaping continuous traits and evolutionary adaptation.
View Article and Find Full Text PDFBiochem Pharmacol
September 2025
Department of Hepatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address:
The gut-liver axis constitutes a bidirectional communication network that integrates the ecological microenvironment, metabolism, and immune signals between the gut and liver systems. Currently, there is compelling evidence indicating that the overall dysfunction of the gut-liver axis is a pivotal driver in the pathogenesis of advanced liver diseases. This review focuses on the latest research progress regarding various components of the intestinal barrier and how these components contribute to the onset and progression of cirrhosis and its complications.
View Article and Find Full Text PDFInt Immunopharmacol
September 2025
Amity Institute of Pharmacy, Amity University Kolkata, Major Arterial Road, Action Area II, Newtown, Kolkata 700135, West Bengal, India. Electronic address:
Diabetes mellitus (DM) and multiple sclerosis (MS), while affecting metabolic and neurological systems respectively, share convergent immunometabolic pathways. This review synthesizes recent evidence elucidating overlapping mechanisms linking DM and MS, emphasizing metabolic dysfunction and systemic inflammation, with therapeutic potential of lifestyle interventions alongside pharmacotherapy. A comprehensive literature analysis examined shared pathogenesis through recent studies.
View Article and Find Full Text PDF