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Background: Preterm birth causes parenting stress and increases the risk of developmental disorders in children. Our objective was to assess the impact of an early psychological intervention, Triadic parent-infant Relationship Therapy (TRT), on parenting stress, parental mental health and preterm infant development in the motor, language, social, behavioral and emotional domains at a corrected age of 18months.
Methods: Sixty-five families of preterm infants were randomly assigned to the intervention group (n=33) or the control group (n=32). Families of full-term children (n=24) were also recruited. Intervention focused on the triadic relationship and aimed to improve parenting stress by supporting parental mental health to promote infant development. The main outcome was assessed with the Parenting Stress Index Short Form (PSI-SF).
Results: Highly significant differences at 18months were observed for the mother and father in overall PSI-SF scores, with 16.6, and 11.7 points, respectively, in favor of the intervention group. Children in the intervention group demonstrated higher full-scale developmental quotients than the preterm controls (an 8.7-point difference) along with lower scores on behavioral tests (a 5.8-point difference at 18months). At 18months, results for children in the intervention group showed no significant differences compared to the full-term group or were even better.
Conclusions: Our study provides sound evidence for the efficiency of the TRT program to reduce parenting stress and improve parental mental health for both parents, thus fostering the infant's overall development.
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http://dx.doi.org/10.1016/j.earlhumdev.2016.05.007 | DOI Listing |
Omega (Westport)
September 2025
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Pregnancy loss is a traumatic experience, and the quality of care can vary significantly across healthcare settings. However, evidence on the impact of different types of care on psychological outcomes is limited. This study examined the relationship between specialized care for parents experiencing pregnancy or neonatal loss and the level of Prolonged Grief Disorder (PGD) and Post-Traumatic Stress Disorder (PTSD) symptoms, as well as the role of midwifery support, one month post-loss.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Cell Res
September 2025
Institute of Cellular and Organismic Biology, Academia Sinica, Taiwan. Electronic address:
Paclitaxel resistance is a major obstacle to achieving long-term remission in patients with triple-negative breast cancer (TNBC), and effective strategies to overcome drug resistance would have significant clinical impact. In this study, we established a paclitaxel-resistant cell clone, T50R, from the human TNBC cell line MDA-MD-231. Intriguingly, these drug-resistant T50R cells required paclitaxel for proliferation.
View Article and Find Full Text PDFJ Pediatr Nurs
September 2025
Department of Nursing, Faculty of Health Sciences, Ankara Medipol University, Ankara, Türkiye.
Purpose: The objective of this scoping review was to systematically map, categorize, and synthesize the existing research identifying the factors associated with the development of medical traumatic stress in pediatric patients receiving clinical care.
Methods: This review followed the methodological framework proposed by Booth et al. (2021) and adhered to the PRISMA-ScR guidelines.
Cien Saude Colet
August 2025
Escuela de Psicología, Facultad de Ciencias Sociales y Comunicaciones, Universidad Santo Tomás. Av. Ejército 146, Centro. 8320073 Santiago Chile
The objective of this study was to evaluate the joint or synergistic (interaction) effect of psychological control, parental knowledge, and posttraumatic stress on the mental health of adolescents who experienced a massive forest fire. A non-experimental, cross-sectional design was used to survey 292 Chilean adolescents (Mean age = 14.39, 51.
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