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Article Abstract
The UK Biobank (UKB) has recently released genotypes on 152,328 individuals together with extensive phenotypic and lifestyle information. We present a new phasing method, SHAPEIT3, that can handle such biobank-scale data sets and results in switch error rates as low as ∼0.3%. The method exhibits O(NlogN) scaling with sample size N, enabling fast and accurate phasing of even larger cohorts.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926957 | PMC |
| http://dx.doi.org/10.1038/ng.3583 | DOI Listing |
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