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Accurate sex estimation is important in forensic investigation to determine the identity of unknown individuals. The aim of this study was to investigate the accuracy of sex assessment based on measurements of the second cervical vertebra (C2) using computed tomographic (CT) images in a Japanese population and to develop discriminant function formulae. The data were collected from 224 Japanese cadavers (112 male subjects, 112 female subjects) on which postmortem CT scanning and subsequent forensic autopsy were performed. Nine CT measurements of the C2 were performed for CT images of each subject. The measurements were assessed using descriptive statistics and discriminant function analyses (DFA). All of the measurements demonstrated significant sexual dimorphism. Multiple DFA with stepwise variable selection resulted in multivariable models; a five-variable model reached an accuracy rate of 92.9%. Our results suggest that metric analysis based on CT images of the C2 can accurately determine the sex from the human skeletal remains in a contemporary Japanese population and may be useful for sex estimation in forensic anthropology.
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http://dx.doi.org/10.1016/j.forsciint.2016.04.010 | DOI Listing |
Geohistorical events are among the most important factors determining population genetic structure. The Sea of Japan is an intriguing area because of its connection to neighboring seas via shallow straits (< 140 m deep) and the occurrence of deep-water anoxic events during glacial periods. Despite repeated anoxic events, species with low dispersal capabilities have been reported at depths deeper than the straits in both the Sea of Japan and the Pacific Ocean.
View Article and Find Full Text PDFBJUI Compass
September 2025
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine Kyoto University Kyoto Kyoto Japan.
Objectives: To develop a novel risk score (RS) model to predict the probability of progression to castration-resistant prostate cancer (PCa) (CRPC) after intensity-modulated radiation therapy (IMRT) for patients with high- and very high-risk PCa according to the National Comprehensive Cancer Network (NCCN) risk classification, since accurate prediction of the clinical outcome of definitive radiation therapy for patients with high- and very high-risk PCa remains challenging due to its heterogeneity.
Materials And Methods: We conducted a retrospective review of 600 patients with high- and very high-risk PCa treated with IMRT at our institution. They were randomly divided into discovery (n = 300) and validation (n = 300) cohorts.
Bull Entomol Res
September 2025
Insect Biosystematics Laboratory, Department of Agricultural Biotechnology, Seoul National University, Seoul, Korea.
This study presents the first record of Kanturski & Lee, 2024 (Aphididae: Lachninae) in South Korea, thereby extending its known distribution beyond Japan and identifying a new host plant, (Rosaceae). We describe diagnostic morphological traits across multiple life stages and compare them with those of Japanese populations. Comparative analyses with Japanese populations demonstrated consistent morphological differentiation, notably elevated ratios of the ultimate rostral segment to antennal segments across multiple morphs in the Korean population, indicating potential ecological adaptation.
View Article and Find Full Text PDFNat Commun
September 2025
Department of Gastroenterology and Hepatology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo, Japan.
The maternal microbiome during pregnancy and the peripartum period plays a critical role in maternal health outcomes and establishing the neonatal gut microbiome, with long-term implications for offspring health. However, a healthy microbiome during these key periods has not been definitively characterized. This longitudinal study examines maternal and neonatal microbiomes using 16S rRNA amplicon sequencing in a Japanese cohort throughout pregnancy and the postpartum period.
View Article and Find Full Text PDFCNS Drugs
September 2025
Global Health Neurology Lab, Sydney, NSW, 2150, Australia.
Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
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