Acid-mediated topological control in a functionalized foldamer.

Chem Commun (Camb)

Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK. and Department of Chemistry, New York University, New York, New York 10003, USA.

Published: May 2016


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Article Abstract

Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.

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http://dx.doi.org/10.1039/c6cc01496hDOI Listing

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Acid-mediated topological control in a functionalized foldamer.

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