98%
921
2 minutes
20
In this study we describe the first isolation of Mycobacterium triplex in Latin America. This species causes infections in humans, with very few reports from around the world. We isolated two sputum specimens of a patient with a 6-year history of human immunodeficiency and tuberculosis treatment failure. All tests used confirmed M. triplex and the patient responded well to drug therapy for 18months.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.ijmyco.2015.09.004 | DOI Listing |
Respir Med
November 2019
Metro South Clinical Tuberculosis Service, Brisbane, Queensland, Australia; University of Queensland, Brisbane, Queensland, Australia; Gallipoli Medical Research Institute, Brisbane, Queensland, Australia; Greenslopes Private Hospital, Brisbane, Queensland, Australia.
Objectives: Mycobacterium triplex is a slow-growing nontuberculous mycobacteria (NTM) and is a rare cause of human disease. The pathogenicity, natural history and spectrum of disease is unknown. The aim of this study was to review the clinical features, outcomes and drug susceptibility testing (DST) of all M.
View Article and Find Full Text PDFIDCases
October 2019
Respiratory Disease Center, Tazuke Kofukai Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka 530-8480, Japan.
() is a bacterial species that can cause severe pulmonary diseases. Despite its clinical importance, only a few cases of infection have been reported. Here, we present a rare case of pulmonary disease due to in an immunocompetent patient who showed abnormal findings on chest X-ray and computed tomography scans.
View Article and Find Full Text PDFChembiochem
January 2019
Department of Chemistry and Biochemistry, School of Green Chemistry and Engineering, The University of Toledo, 2801 West Bancroft Street, Toledo, Ohio, 43606, USA.
α,α'-Trehalose plays roles in the synthesis of several cell wall components involved in pathogenic mycobacteria virulence. Its absence in mammalian biochemistry makes trehalose-related biochemical processes potential targets for chemotherapy. The trehalose 6-phosphate synthase (TPS)/trehalose 6-phosphate phosphatase (TPP) pathway, also known as the OtsA/OtsB2 pathway, is the major pathway involved in the production of trehalose in Mycobacterium tuberculosis (Mtb).
View Article and Find Full Text PDFJMM Case Rep
May 2018
University of Queensland, Brisbane, Queensland, Australia.
Introduction: We describe the first detailed case report of human infection with . Infection with non-tuberculous mycobacteria (NTM) related to is well described, despite the lack of previous confirmed reports of related human disease. Localised cervical lymphadenitis is the most common NTM disease in children, with species closely related to such as and , having been shown to be rare causative agents.
View Article and Find Full Text PDFClin Microbiol Infect
June 2018
Respiratory Disease Centre, Fukujuji Hospital, Japan Anti-Tuberculosis Association, Tokyo, Japan.