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Hypotony maculopathy is a condition that may result in visual deterioration from choroidal folds or optic disc edema. Optic disc edema can result from altered translaminar pressure gradients (lowered intraocular pressure, increased cerebrospinal fluid pressure, or increased orbital pressure). We report a case of bilateral optic disc edema in a patient with glaucoma and thyroid-related orbitopathy. The patient's disc edema was initially presumed to be secondary to her orbitopathy, but persisted after bilateral orbital decompression. Ultimately, disc edema and choroidal folds in the right eye resolved after trabeculectomy revision and an increase in intraocular pressure. This case serves as a reminder of the causes of optic disc edema and demonstrates delayed reversal of hypotony maculopathy.
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http://dx.doi.org/10.1159/000441121 | DOI Listing |
BMJ Case Rep
September 2025
Neurology, Father Muller Medical College, Mangalore, Karnataka, India.
A man in his 30s presented with sudden vision loss in the right eye and diminished vision in the left eye accompanied by headache. Clinical findings included bilateral disc oedema, reduced visual acuity in both eyes (right eye>left eye), dense premacular haemorrhage in the right eye and impaired colour vision. Blood tests were positive for serum myelin oligodendrocyte glycoprotein (MOG) antibodies, confirming MOG-associated optic neuritis (ON).
View Article and Find Full Text PDFCan J Ophthalmol
September 2025
Department of Ophthalmology, Université de Montréal, Montreal, QC, Canada; Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Objective: Boston keratoprosthesis (KPro) plays an important role in treating complex corneal disease but is associated with many complications. This study addresses correlations and trends found in KPro patients, to understand the evolution and optimize postoperative care to minimize complications.
Design: A retrospective case series analyzing outcomes and evolution over 15 years.
Cureus
July 2025
Radiation Oncology, Indraprastha Apollo Hospital, New Delhi, IND.
The management of localized choroidal melanoma generally involves definitive radiation therapy when globe preservation is feasible. Stereotactic radiosurgery (SRS) using the Gamma Knife system (Elekta AB, Stockholm, Sweden) or the CyberKnife system (Accuray Inc., Madison, WI, USA) is a well-established radiation modality for treating choroidal melanoma, with outcomes comparable to those of other radiation techniques.
View Article and Find Full Text PDFAm J Trop Med Hyg
August 2025
Department of Ophthalmology, Marshfield Clinic Health Center, Marshfield, Wisconsin.
Three adult patients with unilateral optic neuropathy, seropositive for Jamestown Canyon virus (JCV) IgM and acute infection, experienced acute unilateral vision loss. Two cases had swollen optic nerves with vision loss in a pattern suggestive of papillitis, whereas the third had retrobulbar optic neuritis. All presented with vision loss rather than typical meningoencephalitis symptoms (e.
View Article and Find Full Text PDFReports (MDPI)
August 2025
Department of Ophthalmology, Zagreb University Hospital Center, 10 000 Zagreb, Croatia.
: Ischemic optic neuropathies (IONs) are significant causes of vision loss resulting from compromised blood flow to the optic nerve. Diabetes mellitus (DM) exacerbates the risk of IONs through chronic hyperglycemia and associated vascular dysfunction. Recently, semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has been linked to ocular complications, including non-arteritic anterior ischemic optic neuropathy (NAION), potentially due to the rapid glycemic changes or vascular effects.
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