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Unlike traditional rigid actuators, the significant features of Series Elastic Actuator (SEA) are stable torque control, lower output impedance, impact resistance and energy storage. Recently, SEA has been applied in many exoskeletons. In such applications, a key issue is how to realize the human-exoskeleton movement coordination. In this paper, double closed-loop cascade control for lower limb exoskeleton with SEA is proposed. This control method consists of inner SEA torque loop and outer contact force loop. Utilizing the SEA torque control with a motor velocity loop, actuation performances of SEA are analyzed. An integrated exoskeleton control system is designed, in which joint angles are calculated by internal encoders and resolvers and contact forces are gathered by external pressure sensors. The double closed-loop cascade control model is established based on the feedback signals of internal and external sensor. Movement experiments are accomplished in our prototype of lower limb exoskeleton. Preliminary results indicate the exoskeleton movements with pilot can be realized stably by utilizing this double closed-loop cascade control method. Feasibility of the SEA in our exoskeleton robot and effectiveness of the control method are verified.
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http://dx.doi.org/10.3233/THC-151058 | DOI Listing |
MethodsX
December 2025
Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
This method presents a double-blind, randomized, parallel-group clinical trial aimed at personalizing cranial electrotherapy stimulation (CES) according to individual brain signals, assessing the effect of Intelligent Closed-Loop Cranial Electrotherapy Stimulation (IC-CES) on Major Depressive Disorder (MDD). To evaluate the effectiveness of IC-CES in treating MDD. 120 participants were randomly assigned to either the IC-CES group or the CES group.
View Article and Find Full Text PDFDiabetes Technol Ther
August 2025
Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom.
To evaluate trends in insulin delivery and day-to-day variability of insulin requirements over 48 months of hybrid closed-loop use following diagnosis of type 1 diabetes (T1D) in individuals aged 10-16 years. A secondary analysis of the closed-loop arm of an open-label, multicenter, randomized, parallel hybrid closed-loop trial assessing closed-loop insulin delivery in newly diagnosed children and adolescents with T1D was conducted. Mean total daily dose (TDD) over 24 h and during the night, as well as mean total basal and bolus insulin over 24 h, were calculated.
View Article and Find Full Text PDFEndocr Pract
August 2025
Department of Endocrinology and Nutrition, Hospital Universitario de Badajoz, Badajoz, Spain; Universidad de Extremadura, Badajoz, Spain.
Objective: The main challenge in type 1 diabetes mellitus management is achieving and maintaining glycemic control. Hybrid closed-loop (HCL) systems offer patients the potential to safely achieve tight glycemic targets. This study analyzed the clinical and economic impact of HCL systems compared with intermittently scanned continuous glucose monitoring (is-CGM) and continuous subcutaneous insulin infusion (CSII) therapy from the Spanish health care system perspective.
View Article and Find Full Text PDFMicromachines (Basel)
July 2025
School of Mechanical and Electrical Engineering, Guilin University of Electronic Technology, Guilin 541004, China.
Silicon carbide (SiC) half-bridge power modules are widely utilized in new energy power generation, electric vehicles, and industrial power supplies. To address the research gap in collaborative validation between electro-thermal coupling models and process reliability, this paper proposes a closed-loop methodology of "design-simulation-process-validation". This approach integrates in-depth electro-thermal simulation (LTspice XVII/COMSOL Multiphysics 6.
View Article and Find Full Text PDFSci Rep
July 2025
Faculty of Electronics, Photonics and Microsystems, Department of Field Theory, Electronic Circuits and Optoelectronics, Wrocław University of Science and Technology, Wyb. Wyspiańskiego 27, 50-370, Wrocław, Poland.
The thermal degradation of polymers in powder bed fusion (PBF) is one of the major issues preventing wider adoption of this technology at the production scale. Although standard PBF allows for elastic production of complex parts in a single-step manufacturing process, it is materially inefficient. This is because only approximately 10% of the material is used to develop parts, while the majority of semicrystalline polyamide 12 (PA12) remain unused.
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