Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.plrev.2015.07.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A thorny tale: The origin and diversification of Cirsium (Compositae).
Mol Phylogenet Evol
March 2025
Autonomous University of Barcelona, Systematics and Evolution of Vascular Plants (UAB) - Associated Unit to CSIC by IBB - Cerdanyola del Vallès, Spain.
Widely distributed plant genera offer insights into biogeographic processes and biodiversity. The Carduus-Cirsium group, with over 600 species in eight genera, is diverse across the Holarctic regions, especially in the Mediterranean Basin, Southwest Asia, Japan, and North America. Despite this diversity, evolutionary and biogeographic processes within the group, particularly for the genus Cirsium, remain underexplored.
View Article and Find Full Text PDFToxicity Adaptive Lists Design: A Practical Design for Phase I Drug Combination Trials in Oncology.
JCO Precis Oncol
October 2024
Dana-Farber Cancer Institute, Boston, MA.
Purpose: We introduce a novel algorithmic approach to design phase I trials for oncology drug combinations.
Methods: Our proposed Toxicity Adaptive Lists Design (TALE) is straightforward to implement, requiring the prespecification of a small number of parameters that define rules governing dose escalation, de-escalation, or reassessment of previously explored dose levels. These rules effectively regulate dose exploration and control the number of toxicities.
A tale of two constructs: combined assessment of demoralization and subjective incompetence.
Psychol Health Med
October 2024
Institute of Psychiatry, Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.
Demoralization comprises multiple dimensions. Among them, Subjective Incompetence (SI) is the perception of being incapable of appropriate action in demanding circumstances. SI may be an early sign of demoralization preceding hopelessness, thus we aimed at integrating items related to Subjective Incompetence into the clinical assessment of demoralization.
View Article and Find Full Text PDFAncient Rapanui genomes reveal resilience and pre-European contact with the Americas.
Nature
September 2024
Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Rapa Nui (also known as Easter Island) is one of the most isolated inhabited places in the world. It has captured the imagination of many owing to its archaeological record, which includes iconic megalithic statues called moai. Two prominent contentions have arisen from the extensive study of Rapa Nui.
View Article and Find Full Text PDFNonlinear bias toward complex contagion in uncertain transmission settings.
Proc Natl Acad Sci U S A
January 2024
Vermont Complex Systems Center, University of Vermont, Burlington, VT 05401.
Current epidemics in the biological and social domains are challenging the standard assumptions of mathematical contagion models. Chief among them are the complex patterns of transmission caused by heterogeneous group sizes and infection risk varying by orders of magnitude in different settings, like indoor versus outdoor gatherings in the COVID-19 pandemic or different moderation practices in social media communities. However, quantifying these heterogeneous levels of risk is difficult, and most models typically ignore them.
View Article and Find Full Text PDF