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Headache may be caused by primary disorders, such as migraines, or secondary disorders, such as intracranial neoplasm or hemorrhage. Imaging plays an important role in differentiating between primary and secondary headache disorders. This article reviews the effectiveness of computed tomography (CT) and magnetic resonance imaging (MRI) in the evaluation of a patient with a headache. It also discusses the utility and cost-effectiveness of performing imaging studies in patients with a headache and a normal neurological exam. Emerging imaging techniques such as functional MRI, positron emission tomography (PET) scans, and voxel-based morphometry (VBM) are also discussed.
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http://dx.doi.org/10.1007/s11916-015-0490-3 | DOI Listing |
CNS Drugs
September 2025
Global Health Neurology Lab, Sydney, NSW, 2150, Australia.
Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
View Article and Find Full Text PDFDermatol Surg
September 2025
Etre Cosmetic Dermatology and Laser Center, New Orleans, Louisiana.
Background: Botulinum neurotoxins in aesthetic medicine require reconstitution, which may cause administration errors.
Objective: To evaluate liquid nivobotulinumtoxinA treatment of lateral canthal lines (LCL) and glabellar lines (GL).
Materials And Methods: Participants with moderate-to-severe LCL with/without moderate-to-severe GL were enrolled in 2 double-blind randomized clinical trials.
Afr J Prim Health Care Fam Med
August 2025
Department of Health Studies, College of Human Science, University of South Africa, Pretoria, South Africa; and Department of Public Health, School of Health Science, Shashemene Campus, Madda Walabu University, Shashemene.
Background: Malaria is a leading cause of morbidity, mortality and socio-economic burden in Ethiopia. Although the country set a goal to eradicate malaria by 2030, a resurgence has been reported recently.
Aim: This study was conducted to assess the signs of malaria, its symptoms and knowledge regarding prevention and its associated factors among rural Ethiopians.
Headache
September 2025
Hartford HealthCare Headache Center, Ayer Neuroscience Institute, University of Connecticut, West Hartford, Connecticut, USA.
Objective: (1) To estimate the impact of migraine on work productivity among employees at a large healthcare system in the United States. (2) To assess the knowledge and perception of migraine among employees and to evaluate the number of employees interested in receiving migraine care to help plan a future workplace migraine education and management program.
Background: Despite advances in treatment, migraine is underdiagnosed and undertreated and remains a leading cause of disability in the world.
Medicine (Baltimore)
September 2025
Department of Anesthesiology, Nan'an Hospital, Quanzhou City, China.
Pain, frailty, and the use of analgesic medications often occur together. Previous studies have demonstrated a strong link between them. The purpose of this study was to investigate the causal effects of pain and analgesic medication on frailty.
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