Effectiveness of Evidence-Based Congestive Heart Failure (CHF) CPOE Order Sets Measured by Health Outcomes.

Objective: Evidence-based order sets for treatment of patients with common conditions promise ordering efficiency and more consistent health outcomes. Despite ongoing utilization of order sets, quantitative evidence of their effectiveness is lacking. This study quantitatively analyzed benefits of CHF order sets as measured by mortality, readmission, and length of stay (LOS) outcomes.

Methods: Mortality and readmissions were analyzed by comparing "order set" and "free text" groups of adult patients using logistic regression, Pearson chi-squared, and Fisher's exact methods. LOS was calculated by applying One-Way ANOVA and Mann-Whitney tests, supplemented by comorbidity analysis via Charlson Comorbidity Index.

Results: CHF orders placed via sets were effective in reducing mortality [OR=1.818;95% CF 1.039-3.181;p=0.034] and LOS [F(1,10938)=8.352,p=0.013,4.75 days ("free text" group) vs. 5.46 days ("order set" group)], while readmission outcome was not significant [OR=0.913;95% CF 0.734-1.137;p=0.417].

Conclusion: Evidence-based medication ordering practices to treat CHF have potential to reduce mortality and LOS, without effect on readmissions.