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Reduction patterns of Plasmodium falciparum and P. vivax malaria transmission and the role of an integrated strategy of case management and vector control are compared between different ecological zones. The epidemiology of malaria in Hainan and Yunnan provinces was disparate, even though distinct malaria control strategies have been adapted to different situations based on risk group, vector behaviours, local health infrastructure, and environmental conditions. The island Hainan appears to be victorious in eliminating malaria. However, there is still a long way to go to prevent the reintroduction of malaria in Hainan province and eliminating malaria in the border areas of Yunnan province. This review of the experiences and challenges from malaria control to elimination in Hainan and Yunnan provinces of southern China will provide a basis for the future elimination of malaria in the whole country.
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http://dx.doi.org/10.1016/B978-0-12-800869-0.00003-2 | DOI Listing |
Parasite
September 2025
Parasitology Department, São Paulo University, 1374 Av. Prof. Lineu Prestes, São Paulo, State of São Paulo 05508-000, Brazil.
Understanding why Diptera, such as mosquitoes and sand flies, feed on humans is crucial in defining them as vectors of diseases such as malaria, dengue fever, Zika virus, and leishmaniasis. Determining their attraction to humans (anthropophily) helps in assessing the risk of disease transmission, designing effective vector control strategies, and monitoring the effectiveness of existing control measures. An important question is whether they are specifically attracted to humans in preference to other mammals or whether there is something else at play.
View Article and Find Full Text PDFOpen Life Sci
August 2025
Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.
The present study aimed to evaluate the therapeutic potential of with silver nanoparticles (AgNPs) and chloroquine (CQ) 10 mg/kg in treating lung inflammation caused by infection in a mouse model. Fifty female C57BL/6 mice were divided into five groups: control, leaf extract (IOLE) AgNPs treated, infected, infected and IOLE AgNPs treated, infected and CQ 10 mg/kg treated. Lung histopathology was assessed using microscopic analysis and immunohistochemistry investigation for TNF-α and IL-6.
View Article and Find Full Text PDFFront Public Health
September 2025
College of Medicine and Health Sciences, Arbaminch University, Arbaminch, Ethiopia.
Background: Long-lasting insecticidal nets (LLINs) are the main vector control tools and remain protective against malaria, even in the presence of high pyrethroid resistance. However, in sub-Saharan Africa, the estimated percentage of the population sleeping under LLINs is low. Hence, this qualitative study was conducted to explore perceptions about LLINs and the reasons for low LLIN use in southern Ethiopia.
View Article and Find Full Text PDFJ Parasitol Res
August 2025
Department of Biology, Wachemo University, Hossana, Ethiopia.
Environmental changes due to global warming and human activities have negatively impacted malaria vector control in Hadiya zone, Ethiopia. Plants contain anthraquinoes. Flavonoids, glycosides, phenol, saponin, steroids, tannin, and terpenes that are target specific, rapidly biodegradable, ecofriendly, and less toxic to human health.
View Article and Find Full Text PDFActa Trop
September 2025
Guangdong Provincial Key Laboratory of Aquatic Economic Animals, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China;. Electronic address:
Malaria is still one of the most important parasitic diseases with millions of cases reported globally every year. Combination therapies of artemisinin or its derivatives, with a partner drug, are the first-and second-line treatments for malaria. However, recently, artemisinin partial resistance or tolerance has emerged and emphasizes the need for new therapeutic approaches to malaria.
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