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Rock art compels interest from both researchers and a broader public, inspiring many hypotheses about its cultural origin and meaning, but it is notoriously difficult to date numerically. Barrier Canyon-style (BCS) pictographs of the Colorado Plateau are among the most debated examples; hypotheses about its age span the entire Holocene epoch and previous attempts at direct radiocarbon dating have failed. We provide multiple age constraints through the use of cross-cutting relations and new and broadly applicable approaches in optically stimulated luminescence dating at the Great Gallery panel, the type section of BCS art in Canyonlands National Park, southeastern Utah. Alluvial chronostratigraphy constrains the burial and exhumation of the alcove containing the panel, and limits are also set by our related research dating both a rockfall that removed some figures and the rock's exposure duration before that time. Results provide a maximum possible age, a minimum age, and an exposure time window for the creation of the Great Gallery panel, respectively. The only prior hypothesis not disproven is a late Archaic origin for BCS rock art, although our age result of A.D. ∼ 1-1100 coincides better with the transition to and rise of the subsequent Fremont culture. This chronology is for the type locality only, and variability in the age of other sites is likely. Nevertheless, results suggest that BCS rock art represents an artistic tradition that spanned cultures and the transition from foraging to farming in the region.
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http://dx.doi.org/10.1073/pnas.1405402111 | DOI Listing |
PLoS One
September 2025
College of Landscape Architecture and Art, Northwest Agriculture and Forestry University, Xianyang, China.
This study investigates the spatial and temporal distribution and the influencing factors of 579 cultural heritage sites along the Qin-Shu Ancient Road in Shaanxi Province, employing kernel density estimation, buffer analysis, and geographic detectors. Three key findings emerge: (1) The spatial pattern is characterized by a "line-belt-core" structure, with a belt-like aggregation along the Xi'an-Baoji-Hanzhong axis. Core concentrations are found in Xi'an (181 sites), Hanzhong (159 sites), and Ankang (122 sites), with secondary concentrations in Baoji (72 sites) and Shangluo (36 sites).
View Article and Find Full Text PDFSci Adv
September 2025
Department of Anthropology, University of Florida, Gainesville, FL 32611, USA.
Domestic equids were central to the initial colonization of the Atlantic coast of the Americas, a process partially chronicled by historical records. While Spanish colonists brought horses to the Caribbean decades earlier, settlement of the English colony at Jamestown, Virginia, was among the first dispersals of horses to the eastern seaboard. Archaeozoological analysis of identifiable domestic equid remains from two contexts associated with the initial occupation of Jamestown demonstrates intense processing and consumption of the first Jamestown horses during the "Starving Time" winter of 1609.
View Article and Find Full Text PDFMed Phys
September 2025
Ion Beam Applications (IBA), Chemin du Cyclotron 3, Louvain-la-Neuve, Belgium.
Background: To maximize the potential benefit of the FLASH sparing effect during treatment, normal tissue regions would ideally be irradiated only briefly, typically for a couple of hundred milliseconds. Achieving such fast proton irradiation involves a mono-energetic beam at the highest cyclotron energy and the use of 3D-printed conformal energy modulators (CEM). In ConformalFLASH, a dedicated snout is mounted on the nozzle, containing the CEM, a range shifter, and an aperture.
View Article and Find Full Text PDFTrends Mol Med
August 2025
Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of International Health, Johns Hopkins Bloomberg Schoolof Public Health, Baltimore, MD, USA; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School
Antiretroviral therapy (ART) has transformed HIV infection into a chronic, manageable condition; however, people living with HIV (PLWH) have an increased risk of atherosclerotic cardiovascular disease (ASCVD). Impaired cholesterol efflux due to dysfunction of macrophage lipid transporters and high-density lipoprotein (HDL) is an important mechanism in HIV-associated atherosclerosis. HIV Nef protein inhibits ATP-binding cassette transporter (ABC)A1-mediated cholesterol efflux via post-transcriptional downregulation, mislocalization, and enhanced degradation.
View Article and Find Full Text PDFAppl Radiat Isot
November 2025
Department of Physics, Faculty of Science, Atatürk University, Erzurum, Turkey.
This study aims to investigate the physical, structural, and radiation shielding properties of four rock types commonly used in natural cement, including clay, granite, and quartz originating from the Hakkâri region of Turkey. Structural characterization was performed using ICP-MS, XRD, and FT-IR analyses. At the same time, radiation shielding effectiveness was determined through measurements of mass attenuation coefficient (MAC), linear attenuation coefficient (LAC), half-value layer (HVL), mean free path (MFP), effective atomic number (Zeff), energy buildup factor (EBF), and fast neutron removal cross-section (R) within the energy range of 80.
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