Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/cid/ciu562 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Efficacy and activity of gepotidacin against bacterial uropathogens, including drug-resistant phenotypes, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3).
Antimicrob Agents Chemother
September 2025
GSK, London, United Kingdom.
Two recent Phase 3 trials demonstrated the efficacy of gepotidacin compared with nitrofurantoin to treat uncomplicated urinary tract infections (uUTIs) in females. Pretreatment urine specimens were obtained from all participants. Based on pooled trial data (treatment groups combined), central laboratory culture results identified 1,421 (45%) participants with ≥1 baseline qualifying (≥10 CFU/mL) uropathogen (i.
View Article and Find Full Text PDFA Rapid Approach for Assessing Body Fluid Matrix Effects.
J Appl Lab Med
September 2025
Department of Pathology, UC San Diego Health, San Diego, CA, United States.
Background: While clinical laboratories routinely perform automated chemistry assays on approved specimens (e.g., plasma and serum), the FDA has not evaluated the validity of these assays for nonapproved specimens (e.
View Article and Find Full Text PDFComparative effect of Zircos-E and airborne-particle abrasion on zirconia surface treatment: A meta-analysis.
J Prosthodont
September 2025
Department of Prosthodontics, Faculty of Dentistry, Ataturk University, Erzurum, Turkey.
Purpose: Debonding of zirconia restorations remains a significant clinical challenge due to its glass-free microstructure, which limits micromechanical and chemical adhesion. Zircos-E, a nitric-hydrofluoric acid mixture, has been proposed as a simplified room-temperature alternative to airborne-particle abrasion (APA). This meta-analysis aimed to compare the shear bond strength (SBS) of zirconia surfaces treated with Zircos-E etching versus APA.
View Article and Find Full Text PDFA sensitive and specific non-invasive urine biomarker panel for prostate cancer detection.
EBioMedicine
August 2025
Department of Neurosurgery and Oncology, Sidney Kimmel Comprehensive Cancer Center, School of Medicine, Johns Hopkins University, 1650 Orleans St., Baltimore, MD, 21231, USA; Johns Hopkins All Children's Hospital, 600 5th St. South, St. Petersburg, FL, 33701, USA. Electronic address:
Background: Prostate cancer (PCa) is one of the leading causes of cancer death in men. While prostate-specific antigen (PSA) testing is widely used for screening, its diagnostic accuracy is limited, often failing to distinguish between benign and malignant prostate conditions, underscoring the need for novel biomarkers with improved diagnostic performance. This study aimed to identify and validate a panel of urinary RNA biomarkers with improved diagnostic accuracy for PCa.
View Article and Find Full Text PDFParticipant acceptability questionnaire results from the Meatal swab Yourself with Testing for Infections Collectively (MYSTIC) study: a diagnostic accuracy study of rectal and pharyngeal swabs pooled with meatal swabs, or first-catch urine, for gonorrhoea and chlamydia detection.
Sex Transm Infect
September 2025
Genitourinary Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Objective: To assess the views of men who have sex with men (MSM) and transgender women (TGW) on acceptability of using meatal swabs compared with first-catch urine (FCU), and acceptability and accuracy of pooling three-site samples compared with individually analysed samples, for gonorrhoea and chlamydia detection, using a questionnaire.
Methods: Prospective, convenience, sample of MSM/TGW attending UK sexual health clinic. Randomised order of self-taken samples from the pharynx and rectum, plus self-taken penile-meatal swab and FCU, for gonorrhoea and chlamydia detection.