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http://dx.doi.org/10.1038/nature13523 | DOI Listing |
PLoS One
September 2025
Department of Maths and Computer Science, Faculty of Science, University of Kinshasa, Kinshasa, The Democratic Republic of the Congo.
Reliable and timely fault diagnosis is critical for the safe and efficient operation of industrial systems. However, conventional diagnostic methods often struggle to handle uncertainties, vague data, and interdependent multi-criteria parameters, which can lead to incomplete or inaccurate results. Existing techniques are limited in their ability to manage hierarchical decision structures and overlapping information under real-world conditions.
View Article and Find Full Text PDFJ Genet Couns
October 2025
Department of Genetic Counseling, Graduate School of Medical Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Newborn screening (NBS) for Fabry disease (FD) is an effective way to identify individuals with FD before the onset of symptoms, enabling early therapeutic treatment. The classic form of FD typically begins in early childhood or later, but the late-onset form often develops in adulthood. However, FD-NBS identifies positive cases regardless of the expected timing of symptom onset.
View Article and Find Full Text PDFJ Eval Clin Pract
September 2025
Cochrane Taiwan, Taipei Medical University, Taipei, Taiwan.
Background: Chest radiography is often performed preoperatively as a common diagnostic tool. However, chest radiography carries the risk of radiation exposure. Given the uncertainty surrounding the utility of preoperative chest radiographs, physicians require systematically developed recommendations.
View Article and Find Full Text PDFAm J Case Rep
September 2025
Department of Pediatrics, Southwest Healthcare Medical Education Consortium, Temecula, CA, USA.
BACKGROUND Morel-Lavallee lesions (MLLs) are uncommon, closed soft-tissue degloving injuries caused by high-energy trauma that are often missed due to their rarity and delayed presentation, resulting in serious complications. MLLs are particularly missed and underreported in pediatric and adolescent patients. We describe the case of an adolescent MLL occurring in an atypical lesion site at the calf to increase awareness of this diagnosis and associated presentation in this patient group, which can differ from adult presentation and contribute to diagnostic uncertainty that consequently impacts clinical decision-making.
View Article and Find Full Text PDFActa Trop
September 2025
Department of Public Health, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
Congenital toxoplasmosis (CT) due to Toxoplasma gondii, an apicomplexan parasite, leads to significant sequelae in children, foetal losses and neonatal deaths worldwide. This study aimed to assess the burden of CT in Burundi for the year 2020. We used epidemiological and economic data collected in major hospitals in Burundi, the Ministry of Public Health in Burundi and international peer-reviewed literature to estimate the disability-adjusted life years (DALYs) and economic costs spent on prenatal consultations, diagnosis and treatment of toxoplasmosis for pregnant women.
View Article and Find Full Text PDF