[Research progress of nano-hydroxyapatite complexes in bone tissue regeneration].

As the nano-hydroxyapatite is the main inorganic component of bone tissue of the human body, artificial synthesis of nano-hydroxyapatite has attracted the most attention in the field of hard tissue repair. To make up multiple aspects of limitations for nano-hydroxyapatite material itself, nano-hydroxyapatite complexes have been widely evaluated and applied in bone repair. This paper reviewed the common nano-hydroxyapatite complexes and their research progress in bone regeneration. Supported by Research Fund of Science and Technology Committee of Shanghai Municipality (12NM0501600, 13NM1402102) and Medicine and Engineering Cross Project of Shanghai Jiao Tong University (YG2012MS29).